enzymes Flashcards
what is the function of kinases?
transfer of phsophate group from ATP to a specific molecule
what is the function of isomerases and mutases?
rearranges molecule
what is the role of dehydrogenases?
remove water
what is the role of synthases?
catalyses a synthesis process
what is the role of decarboxylases?
removes carboxyl group form organic compounds
what is the role of phosphatases?
removes a phosphate group from a protein
what is the role of phosphorylase?
catalyse additon of phosphate group to an acceptor
what is the role of deaminases?
remove amine group from molecule
what is PDH and how is it activated during exercise?
pyruvate dehydrogenase phosphatase
activated by calcium (released during muscle contraction) and large amounts of pyruvate, CoA and NAD
inhibited by acetyl-CoA
what are McArdles patients missing?
how does it effect them?
missing glycogen phosphorylase so no access to muscle glycogen
rely heavily on fat metabolism as lower amounts of ATP available