Enzyme inhibitors/inducers Flashcards

1
Q

↑ enzyme activity + ↓ drug concentration?
(inducers)

“PC BRAS”

A

PC BRAS

P henytoin
C arbamazepine
B arbiturates
R ifampicin
A lcohol (chronic)
S ulphonylureas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

↓ enzyme activity + ↑ drug concentration?
(inhibitors)

“AODEVICES”

A

AODEVICES

A llopurinol
O meprazole
D isulfiram
E rythromycin
V alproate
I soniazid
C iprofloxacin
E thanol (acute)
S ulphonamides
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

P450 inhibitors?

“SICKFACES.COM-group”

A
Sodium valproate
Isoniazid
Cimetidine
Ketonazole
Fluconazole
Alcohol (binge)
Chloramphenicol
Erythromycin
Sulfonamides (i - inhibitor)
.
Ciprofloxacin
OMEPRAZOLE
METRONIDAZOLE
-
Grapefruit juice
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

P450 inducers?

CRAP-GPS

A

CRAP-GPS induces me to madness

Carbamazepines
Rifampicin
Alcohol (chronic)
Phenytoin
Griseofulvin
Sulphonylurea (u - inducer)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly