Enzyme Flashcards

1
Q

The shorter the time time the higher the enzymatic concentration of the solution

A

Yes

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2
Q

ALP in ref

A

False inc

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3
Q

Order of EM of ALP

A

LBPI

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4
Q

Where the substrate binds

A

Active site

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5
Q

Cavity other than the active site and may bind to regulator molecule

A

Allosteric

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6
Q

Inactive form of enzyme

A

Zymogen/proenzyme

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7
Q

Enzyme portion of enzyme
Enzyme portion of holoenzyme

A

Apoenzyme

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8
Q

Complete and active system

A

Holoenzyme

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9
Q

Substance which the enzyme acts

A

Active site

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10
Q

It catalyze removal of group from substrate without hydrolysis

A

Lyases

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11
Q

Catalyze the interconversion of geometric,optical , or positional isomers

A

Isomerase

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12
Q

Macroezymes

A

Transaminases and Phosphatases
Amylase and Lipase
GGT and CK
LD

High molecular mass, binds to Ig, Increase with age, not filtered by the kidney

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13
Q

The shorter the time, the higher the concentration

A

Yes

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14
Q

Enzyme that major source Is skeletal muscle, cardiac, liver

A

AST

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15
Q

Enzyme that decreases when organic phosphate is increased

A

Pche (pseudo cholibesterase )

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16
Q

Enzyme that is high if may pancreatitis

A

Amylase

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17
Q

Enzyme na mata sa alcoholism

A

GGT

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18
Q

Enzyme that is high in prostate cancer and rape case

A

ACP

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19
Q

3 enzymes that is AMI markers

A

CKMB, AST,LD

(MYO TROP TICAL)

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20
Q

Enzyme that is high in brrochitis

A

ACE

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21
Q

If mag baba ang enzyme ngaja nagka Karoo ng drug induced hemolotyiv anemia

A

G6PD

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22
Q

Hepatitis in which ma taas ang AST kaysa ALT

A

Ethanol or alcoholic hepatitis

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23
Q

Enyzme na mataas kapag May bone disorder

A

ALP

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24
Q

What will be the CSF pattern pag May bacteri Al sa LD

A

5 4 3 2 1

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25
Q

What is the ALP kapag naka lagay sa ref

A

False inc

26
Q

Ani ilalagay to differentiate Regan from Nagao at na inhibit nya si Nagao

A

L-Leucine

27
Q

Order of electrophoretic mobility of ALP

A

LBPI(Liver, Bone , Placenta, Intestine )

28
Q

Heat stability order (least stable to most stable )

A

BLIP

29
Q

Isoenzyme na napipigilan ng levamisole

A

Liver and Bone

30
Q

Tumataas ang ALP kapag nag bibinata , pag greater 50nyrs old at pag buntis

A

True

31
Q

At what ph active ang ACP

A

5

32
Q

Ano ang mataas ACP or ALP kapag merong leukoerythroblastosis

A

ACP

33
Q

ALT former name

A

SGPT

34
Q

Saan highest ang AST

A

Viral hepatitis

35
Q

LD is highest on this condition

A

Hemolytic disease, pernicious anemia

36
Q

Isoenzyme na may pinakamaraming sources

A

LD 3

37
Q

LD5

A

Skeletal muscle injury (MMMM)

38
Q

LD4

A

Liver(HMMM)
Hepatic injury infammatiin

39
Q

LD3

A

Lungs,lymphocyte, spleen, pancreas
(HHMM)

40
Q

What is the interpretation if 6 band is positive in electrophoresis

A

Impending death

41
Q

LD6

A

Converts methanol anf ethylene glycol

42
Q

Cancer markers

A

LD 2,3,4

43
Q

LD that concurrently increase with LD6

A

LD5

44
Q

LD isoenzyme that is predominant in blood

A

LD 2

45
Q

LD is stable in _______ hrs in room temp

A

48

46
Q

3 enzyme that increases in Bile duct obsruction

A

5N,ALP,GGT

47
Q

Sample in G6PD

A

Red cell hemolysate

48
Q

Product of G6PD that neutralizes

A
49
Q

Enzyme that inactivate light

A

CK

50
Q

Napakalaki

A

Ckmm

51
Q

Enzyme na mataas sa ectopic pregnancy,mumps,pancreatis,peptic ulcer

A

Amylase

52
Q

Ano ang nag iinhibit kay prostatic ACP

A

L tartare

53
Q

Inhibited by L leucine

A

Nagao ALP

54
Q

Alp na na inhibit ni 3M urea

A

Bone

55
Q

Tawag sa unit ng enzyme

A

Katal

56
Q

Relationship of the velocity of enzyme and substrate

A

Michaelis Menten

57
Q

Atleast 3 causes of increase enzyme

A

Removal,necrosis,cell permeability, cancer, tumor

58
Q

Optimal temp of enzyme

A

37

59
Q

Pwede siya mag bind sa enzyme substrate complex

A

Mixed

60
Q

Imhibitor na nag bibind sa active site

A

Competitive

61
Q

Ano ang kailngan for full ezyme activity

A

Cofactor

62
Q

If the cofactor is organic ano ang other name

A

Co enzyme(organic)
Activator(inorganic)