Environmental and Tox Flashcards
What is the formula to convert Celcius to Fahrenheit
(Cx1.8)+32=F
What Medication is contraindicated in cocaine overdose?
Beta-blocker
What ECG effects does Digoxin have
PR interval prolongation, ST depression or T wave inversion/biphasic T wave.
PR interval prolongation is significant and may indicate toxicity
Clinical manifestations of salicylate toxicity include
Respiratory rate increase, headache, vertigo, tinnitus, confusion, sweating and thirst.
Severe symptoms include agitation seizures and coma.
What enzymes are elevated in Heatstroke?
CPK,SGOT, SGPT and LDH
Under what temp is defibrillation not effective
30 C
What blood transfusion reaction can occur within minutes of administration?
Acute Hemolytic reaction
Rapid destruction of donor blood cells by host antibodies.
What is the treatment for acetaminophen poisoning?
N-acetylcysteine (NAC)
Antidote for Coumadin Overdose
Vit K
Antidote for Heparin toxicity
Protamine Sulfate
Lab Value associated with Coumadin and measures the extrinsic pathway.
PT
Lab Value associated with Heparin and measures the intrisic pathway.
PTT
Treatment of Dig toxicity
Digifab, Mag, phenytoin, lidocaine
What is the target urine output for Rhabodo patient’s
100ml/hr
Treatment for malignant hyperthermia
dantoline
At what temp does the ECG progress to sinus brady, PR prolongation, QT prolongation?
32C or 90F
At what temp do Osborne waves present
86F 30C
Define Histotoxic Hypoxia
Deficiency in the alveolar oxygen exhange.
Define hypemic hypoxia
reduction in the oxygen carring capacity of the blood, anemia, hemorrhage
Define stagnant hypoxia
reduced total CO, pooling of blood or restriction of blood flow.
List Organophosphate toxicity medication treatments
Diazepam, atropine, Pralidoxime (2Pam)
ARDS and DIC are a result of what in the hyperthermic patient?
Lysosomal enzymes,
The release of destructive lysosomal enzymes occurs as a result of extensive muscle damage.
What is the antidote for toxic alcohol toxicity?
Fomepizole,
it prevents formation of toxic metabolites
Digitalis toxicity is exacerbated by
Beta Blockers
S/S of ASA toxicity
GI ulcer, tinnitus
Antidote for Iron Poisoning
deferoxamine
what patient presents with possible seizures, elevated anion gap and nystagmus
Ethylene glycol ingestion
Toxic alcohol ingestion
S/S of Iron ingestion that indicates treatment is effective
Urine that it pink in color
Organophosphate exposure causes the overproduction of the neurotransmitter acetylcholine by
Deactivation of the acetylcholinesterase enzyme which is responsible for the break down of acetylcholine
Which drug will require the addition of sodium thiosulfate in the infusion bag to prevent thiocyanate toxicity?
Nitroprusside
Define the temps for hypothermia
Mild 32-35C alert shivering
Moderate 28-32C loss of shivering, lethargy, confusion
Severe 28C bradycardia, hypotension, unconcious
What should be applied to hydrofluoric acid exposure?
Calcium gluconate gel.