Environmental And Nutritional

Question 1

inhibitor of Complex IV in ETC

Cherry red discoloration of skin and mucous membrane

Answer 1

CO poisoning

Question 2

Inhibits ALA dehydratase and ferrochelatase
Microcytic hypochromic anemia
Saturnine gout

Answer 2

Lead poisoning

Question 3

Minamata disease
CNS damage
Behavioral changes

Answer 3

Mercury

Question 4

Poison of Kings
2-8 week post exposure neuropathy
Chronic hyperpigmentation

Answer 4

Arsenic

Question 5

Preferentially toxic to kidneys by ROS production

Itai itai disease- osteoporosis and osteomalacia with associated renal disease

Answer 5

Cadmium

Question 6

Protein > caloric malnutrition 
Steatosis
Atrophy of small bowel and brain
Flaky paint appearance of skin
Flag sign( overall loss of color or alternstknf bands of pale and dark hair)

Answer 6

Kwashiorkor

Question 7

Vitamin synthesized from tryptophan

Answer 7

Niacin

Question 8

Nyctalopia
Squamous metaplasia of lungs
Urolithiasis
Follicular or papular dermatoses

Excess: pseudotumor cerebri

Answer 8

Vitamin A

Question 9

Craniotabes
Frontal bossing
Pectus carinatum
Rachitic rosary
Bowing of legs

Answer 9

Rickets

Question 10

Common bones affected in osteomalacia

Answer 10

Vertebral bodies and femoral neck

Question 11

Humans cannot synthesize vitamin C due to lack of this enzyme

Answer 11

L gulonolactone oxidase

Question 12

Adiposity signals:
Signals energy excess
Anorexigenic
Thermogenesis

Answer 12

Leptin

Question 13

Adiposity signal that stimulates beta oxidation

Answer 13

Adiponectin

Question 14

Orexigenic signal

Answer 14

Ghrelin

Question 15

From pancreatic B cells that prevents weight gain

Answer 15

Amylin