Energy metabolism. Metabolic rate. Regulation of food intake and energy storage Flashcards
Energy metabolism - 1
ANABOLISM
= building up large molecules from small ones
- energy needed
- e.g. protein synthesis
Energy metabolism - 2
CATABOLISM
= breaking down larger molecules into smaller ones
- energy released
- krebs cycle
Energy metabolism - 3
OXIDATIVE PHOSPHORYLATION
electrons from NADH2/FADH2 move through mitochondrial membrane
this pumps proteins in between inner-outer mitochondrial membranes
proton gradient formed
protons flow back into mitochondrial matrix through ATP synthase
ATP synthase makes ADP+Pi = ATP
oxygen = final electron acceptor
Energy metabolism - 4
KREBS CYCLE
mitochondrial matrix
acetyl coa + oxaloacetate -> citric acid
citric acid breaks down releasing energy in form of NADH2/FADH2
help produce ATP
Energy metabolism - 5
fatty acid oxidation
- fatty acids undergo beta oxidation into acetyl coa entering krebs cycle = ATP produced
Energy metabolism - 6
glycolysis
conversion of glucose -> pyruvate
producing ATP/NADH
located in cytoplasm
Energy metabolism - 7
aerobic metabolism
speed = slow
oxygen = yes
products = CO2/H2O
duration = long term
location = mitochondria
ATP yield = 30 ATP
substate = glucose
Energy metabolism - 8
anaerobic metabolism
speed = fast
oxygen = no
products = lactate
duration = short term
ATP yield = 2 ATP
substate = glucose
location = cytoplasm
metabolic rate - 1
BASAL METABOLIC RATE
= energy expenditure when body is at rest
- after fasting for 12 houes
- in a comfortable environment
Metabolic rate - 2
RESTING METABOLIC EFFECT
same as BMR but not under fasting state, accounts for energy during physical activity + digestion
Metabolic rate - 3
THERMIC METABOLIC EFFECT
= energy required to digest/ absorb/ metabolise food
- protein has highest value
Metabolic rate - 4
PHYSICAL METABOLIC RATE
energy expenditure during all forms of movement
- muscle movement = voluntary (excercise)
- non muscle movement = involuntary (shivering)
Metabolic rate - 5
TOTAL METABOLIC RATE
- total energy expenditure in the day
total = BASAL MR + THERMIC MR + PHYSICAL MR
Metabolic rate - FACTOR 1
AGE
- children have higher metabolism
Metabolic rate - FACTOR 2
FITNESS
- muscle tissue burns more calories at rest than fat tissue
- more fitness = more BMR