Endocrinology

Question 1

⬆️TSH, ⬇️T4

Answer 1

Hypothyroidism

Question 2

⬆️TSH, normal T4

Answer 2

Subclinical Hypothyroidism

Question 3

⬇️TSH, ⬆️T4

Answer 3

Hyperthyroidism

Question 4

⬇️TSH, normal T4

Answer 4

Subclinical Hyperthyroidism

Question 5

⬆️PTH, ⬆️Ca, ⬇️PO4

Answer 5

Primary Hyperparathyroidism

Question 6

⬇️Ca, ⬆️PTH

Answer 6

Secondary Hyperparathyroidism

Question 7

⬆️Ca, ⬆️⬆️⬆️PTH

Answer 7

Tertiary Hyperparathyroidism

Question 8

⬇️PTH, ⬆️PTHrP

Answer 8

Malignant Hyperparathyroidism

Question 9

⬇️PTH, ⬇️Ca, ⬆️PO4

Answer 9

Primary Hypoparathyroidism

Question 10

MEN-1

Answer 10

3 P’s

Parathyroid, pancreas (insulinoma), pituitary prolactinaemia/GH

Question 11

MEN-2

Answer 11

TAP

Thyroid, adrenal (phaechromocytoma), parathyroid

Question 12

Autoimmune Polyendocrine Syndrome - Type 1

Answer 12

Addison’s, Hypoparathyroidism, Chronic mucocutaneous candidiasis

Question 13

Autoimmune Polyendocrine Syndrome - Type 2

Answer 13

Addison’s, T1DM, Autoimmune thyroid disease

Question 14

Phaeochromocytoma

Answer 14

Chatecolamine-producing tumours
Refractory hypertension (alpha blockers)

Question 15

⬆️GH, ⬆️IGF-1

Answer 15

Acromegaly

Question 16

⬇️Na, ⬇️Glucose, ⬆️K

Answer 16

Addison’s

Question 17

No cortisol suppression in low or high dex suppression test

Answer 17

Ectopic ACTH - small lung ca

pigmentation, ⬇️K, metabolic alkalosis, ⬆️glucose, weight loss

Question 18

Cortisol suppressed by high dose dex but not low dose dex

Answer 18

Cushing’s disease - ACTH secreting pituitary adenoma➡️ adrenal hyperplasia