Endocrinology Flashcards
T1DM antibodies in childhood
Insulin autoantibodies
Adult T1DM antibodies
GAD65 antibodies
Others
Insulin autoantibodies (IAA)
IA-2
Zinc transporter 8
Tetrasporin-7
2 or more AAB increase risk to 80%
T1DM genetic susceptibility
HLA2 (DR3/DR4)
Increases risk by 50%
Insulin sensitivity factor
100/TDD
CHO ratio
500/total daily does of rapid insulin
Post party inflammatory condition of pituitary with low ACTH
Lymphocytic hypophysitis
Pituitary apoplexy
Bleeding into pituitary tumour
Rx- steroids
Pituitary hormone affected most with radiation treatment
Growth hormone
Sheehan’s syndrome
Infarct of pituitary post partum
Severe HA
low prolactin, can’t breast feed
Cancer drug associated with hypophysitis
Ipilimumab
Pasiriotide
Somatostain analogue
Risk of diabetes
Treatment agranulocytosis with carbimazole
Stop medication Gcsf Broad spectrum abx Propranolol Definitive therepay - radioactive iodine or surgery
Type of radiation for radioactive iodine
Beta irradiation.
Effect of bhcg during pregnancy
Acts like TSH
Sick euthyroid effect
Low t3
Adrenal oncidentaloma
HU < 10 benign
<3cm
Round
Homogenous