Endocrinological Rx

Question 1

Bromocriptine

Answer 1

dopamine agonist
anti-parkinsonian

blocks production & release of GH from pituitary

Used for hyperprolactinemia, acromegaly, early Parkinson’s

A/E: DOPA + Ergot
Dyskinesia
Orthostatic hypotension
Psychosis
Agitated GI, Arrhythmias
Reynauds’

Question 2

Propylthiouracil (PTU)

Answer 2

thioamide derivative
antithyroid

Used for hyperthyroidism & thryoid storm

AE: increased AST/ALT, fatal hepatotoxicity

Question 3

Methiamazole

Answer 3

Used for hyperthyroidism

CI: preg (1st tri)

Question 4

Lugol solution

Answer 4

Iodine replenisher, radiation protectant
antihyperthyroid

Used for hyperthyroidism, thyroid storm & protection of thyroid gland after radiactive iodine tx or radiation exposure emergency

Question 5

Levothyroxine

Answer 5

Synthetic T4

Used for hypothyroidism

Question 6

Liothyronine

Answer 6

Synthetic T3

Used for hypothyroidism

Question 7

USP thyroid

Answer 7

Dessicated thyroid (T3/T4)

Used for hypothyroid

Question 8

Canadgliflozin

Answer 8

SGLT2 inhibitor (increased urinary glucose excretion)
DMII

Question 9

**Liraglutide

Answer 9

GLP-1 receptor agonist (increases insulin secretion)

Used for DMII, obesity

Question 10

Glyburide

Answer 10

sulfonylurea
increases amount of insulin secreted

Used for DMII

*cross-reactivity w/ sulfa abx

Question 11

Metformin

Answer 11

biguanide

increased number & affinity of insulin receptors in peripheral tissues

*1st choice for DMII
No A/E of hypoglycemia

can cause B12 deficiency

Question 12

Pioglitazone

Answer 12

thiazolidinedione antihyperglycemic

usually used in combo w/ metformin or insulin (rarely alone)

DMII

Question 13

Sitagliptin phosphate

Answer 13

DPP-4 inhibitor (increases insulin release)

DMII

Question 14

Insulin (glargine, lispro, regular)

Answer 14

Lispro: short-acting (3-4 hrs)
Regular: intermediate acting (5-7 hrs)
Glargine: long-acting (24 hrs)

DMII & DMI

Question 15

Dulaglutide

Answer 15

GLP-1 receptor agonist (stimulates insulin production)

DMII

Question 16

Exenatide

Answer 16

GLP-1 recepto agonist (increases insulin production)

DMII

Question 17

Thiazolidinedione (TDZ)

Answer 17

DMII

Question 18

**Desmopressin

Answer 18

diabetes insipidus

Question 19

**Testosterone

Answer 19

androgen

Question 20

**Bicalutamide

Answer 20

androgen

Question 21

**Clomiphene

Answer 21

infertility

Question 22

**Fludrocortisone

Answer 22

adrenal?

Question 23

**Somatropin

Answer 23

other

Question 24

**Octreotide

Answer 24

other