Endocrine System Flashcards
Main Functions
- Water balance
- Uterine contractions and milk release
- Growth, metabolism, and tissue maturation
- Ion regulation
- Heart rate and blood pressure regulation
- Blood glucose control
- Immune system regulation
- Reproductive functions control
ligands aka chemical signals
molecules released from one location that move to another location to produce a response
Intracellular chemical signals
produced in one part of a cell, such as the cell membrane, and travel to another part of the same cell and bind to receptors, either in the cytoplasm or in the nucleus
Intercellular chemical signals
released from one cell, are carried in the intercellular fluid, and bind to receptors that are found in other cells, but usually not in all cells of the body
Autocrine chemical signals
intercellular
chemical signals are released by cells and have a local effect on the same cell type. Example: prostaglandin-like chemicals that are secreted in response to inflammation
Paracrine chemical signals
intercellular
chemical signals are released by cells and have effects on other cell types. Example: somatostatin, secreted by the pancreas, inhibits the release of insulin by other cells in the pancreas
Neuromodulators and neurotransmitters
intercelluar
chemical signals are secreted by nerve cells and aid the nervous system. Example: acetylcholine produced during stressful encounters
Pheromones
intercellular
chemical signals are secreted into the environment and modify the behavior and physiology of other individuals. Example: those produced by women can influence the length of the menstrual cycle of other women
Receptors
proteins or glycoproteins chemical signal binds to to produce a response
specificity
only certain chemical signals can bind to a receptor sit e based on shape and chemical characteristics
Types of receptor molecules that respond to intercellular chemical signal
intracellular
membrane-bound
Intracellular receptors
receptors are located in either the cytoplasm or the nucleus of the cell. Signals diffuse across the cell membrane and bind to the receptor sites on intracellular receptors
Membrane-bound receptors
receptors extend across the cell membrane, with their receptor sites on the outer surface of the cell membrane. They respond to intercellular chemical signals that are large, water-soluble molecules that do not diffuse across the cell membrane
Receptors that directly alter membrane permeability
For example, acetylcholine (adrenaline) from nerve fiber endings binds to receptors that are part of the membrane channels for sodium ions
Receptors and G proteins
G proteins (guanine nucleotide-binding proteins) are found on the inner surface of the plasma membrane and function as receptors of hormones. For example, chemical signals include cyclic adenosine monophosphate glycerol and inositol triphosphate that bind to receptor molecules in the cell and alter their activity to produce a response