Endocrine System Flashcards
Master gland, regulates other glands
Pituitary
Gland: circadian rhythm, day/night cycles
Pineal gland
Gland: Stimulates metabolism
Thyroid
Regulates calcium in blood (gland)
Parathyroid
Initiates the immune system (gland)
Thymus
Maintain sodium and potassium balance, cell metabolism, resist stress, produce sex hormones, release adrenaline (gland)
Adrenal gland
Regulates blood sugar (gland)
Pancreas
Produce sex hormones necessary for reproduction (gland)
Gonads
Disorder: excessive drowsiness, disrupted sleep patterns
Hypersecretion of melatonin
Disorder: fertility difficulty
Hyposecretion of melatonin
Disorder: undersecretion of growth hormone, normal proportions with max height of 4 feet
Dwarfism
Growth hormone secreted after growth and development
Acromegaly
Oversecretion of GH, usually caused by pituitary tumor (disorder)
Gigantism
Hyper/hypo-secretion of LH/FSH (disorder)
Sterility
Hyposecretion of of ADH; excessive thirst and urination (disorder)
Diabetes insipidus
Enlarged thyroid gland due to insufficient iodine in diet (disorder)
Goiter
Early childhood disorder, hyposecretion can lead to mental and physical retardation
Cretinism
Hypothyroidism in adults that can lead to fatigue, obesity, dry skin, and low body temperature
Myxedema
Oversecretion resulting in high metabolism, weight loss, rapid heart rate
Hyperthyroidism
Hyperthyroidism resulting in enlarged thyroid, bulging eyes
Grave’s disease
Lack of PTH, uncontrollable muscle spasms, may cause death
Tetany
Causes massive bone destruction
Hyperparathyroidism
No immune system (bubble boy)
Immune deficiency
Hyposecretion, bronzed skin, muscle weakness, suppressed immune system
Addison’s disease
Hypersecretion, tumor in cortex, moonfaced, buffalo hump, high BP, depressed immune system
Cushing’s syndrome
Body does not produce enough insulin; type I and type II
Diabetes mellitus
Sterility, lack of physical development (sexual immaturity)
Hyposecretion of androgen/estrogen
Endocrine system vs. nervous system
Endocrine-slower
Chemical substances secreted by cells that regulate metabolic activity
Hormones
Two chemical classifications of hormones
Amino-based
Steroid-based
4 ways that hormones alter cellular activity
- change membrane permeability
- synthesis of proteins
- activate/inactivate enzymes
- stimulation of mitosis
Three types of hormone release stimuli?
- hormonal
- humoral
- neural
Most common type of stimulus?
Hormonal stimulus
Hormones released due to changes in blood levels of ions and nutrients
Humoral stimulus
In neural stimulus, what causes hormones to be released?
Nerve fiber stimulus
Can a steroid hormone diffuse through the cell membrane?
Yes
In steroid hormone, what does the steroid and receptor bind to?
DNA in the nucleus
In steroid hormone, what does mRNA create?
Synthesis of new protein
Non-steroid hormone must bind to a _____ on the cell membrane
Receptor site
Enzyme reaction in a non-steroid hormone creates a…?
Second messenger molecule
Hypothalamus regulates this gland
Pituitary
Melatonin (gland?)
Pineal
Oxytocin
Pituitary
ADH
Pituitary
GH
Pituitary
PRL
Pituitary
FSH
Pituitary
FSH
Pituitary
Estrogen
Gonads
Mineralcortoids
Adrenal
ACTH
Pituitary
T4
Thyroid
Calcitonin
Thyroid
PTH
Parathyroid
Thymosin
Thymus
Epinephrine
Adrenal
TSH
Pituitary
Insulin, glucagon
Pancreas
Androgen
Gonads
LH
Pituitary
Progesterone
Gonads
Type I diabetes
Pancreas
Dwarfism
Pituitary
Addison’s disease
Adrenal
Tetany
Parathyroid
Graves’ disease
Thyroid
Immune deficiency
Thymus
Myxedema
Thyroid
Type II diabetes
Pancreas
Acromegaly
Pituitary
Goiter
Thyroid
Cushing syndrome
Adrenal
Diabetes insipidus
Pituitary
Gigantism
Pituitary