Chapter 10 Blood Review (Test) Flashcards
Characteristics of leukocytes
WBC Fight against disease Less than 1% blood volume Have nucleus Kill parasitic worms Involved in immune system
Functions of blood
River of life
Maintain electrolytes transports everything the body needs (waste/protein)
Pathways cells can take in hematopoiesis?
Lymphoid–produce lymphocytes
Myeloid–produce all other cells
All cells in your blood; include RBCs, WBCs, and platelets
Formed elements
Where platelets originate from
Megakaryoctes
WBCs ability to move in and out of blood vessels
Diapedesis
RBCs; most numerous cells, about 45% of formed elements aka hematocrit
Erythrocytes
These stem cells are crated in the red bone marrow
Hemocytoblasts
How is blood type determined?
By antigens on plasma membrane
Cell pieces/fragments
Originate from megakaryoctes
IMPORTANT IN CLOTTING
Platelets
Whitish layer between formed elements and plasma
Buffy coat
Chemicals released by damaged tissue to signal
Positive chemotaxis
How long does clotting occur in hemostasis?
3-6 minutes
Which WBCs are granulated/agranulated?
Granulated: neutrophils, basophils, eosinophils
Agranulated: lymphocytes and monocytes
Components of plasma
Water (90%)
Salts and gases
Fibrinogens, globulins, albumin (proteins)
Blood clot attached to blood vessel wall
Thrombus
Floating clot within vessels, bad when reaches heart or lungs
Embolus
Most common blood type?
O Rh+
Disorder where there is not enough platelets and abnormal bleeding
Thrombocytopenia
Colony stimulating factors; stimulates WBC production
CSF
Universal donor?
O
Universal recipient?
AB
Characteristics of blood
pH of 7.35-7.45
Temp. of 100.4
8% of body weight
5-6 liters
Hereditary bleeding disorder due to lack of any clotting factor
Hemophilia
3 phases of hemostasis
Platelet plug formation
Vascular spasm
Coagulation (blood clot)
4 types of blood?
A, B, AB, O
Erythroprotein; hormone released by kidneys that controls RBC formation
EPO
Differences in Rh can cause problems in…
Blood donation and pregnancy (if mom is Rh-)
If you get the wrong blood type, what can occur?
Agglutination-clumping of the blood
What helps to increase clotting?
Gauze and pressure
Disorder with high number of RBCs, increased blood viscosity
Polycythemia
Fe proteins; transports oxygen
Hemoglobin
Percentage breakdown of blood
- 45-46% is formed elements
- > 45% of formed elements are RBCs
- > less than 1% are WBCs
- The other 55% is plasma
Granulated WBCS (granulocytes) 1. active phagocytes that increase rapidly during short term/acute infection What percent do they make up?
Neutrophils, 40-70%
Granulated WBCs (granulocytes)
2. Kill parasitic worms, increase during allergy attacks
Percentage?
Eosinophils, 1-4%
Granulated WBCs, granulocytes
3. Contain histamine which is discharged at the site of inflammation
Percentage?
Basophils, 0-1%
Agranulocytes (WBCs)
1. Part of immune system; involved in graft rejection, fighting tumors and viruses
Lymphocytes; 20-45%
Agranulocytes, WBCs
2. Active phagocytes that become macrophages involved in long-term cleanup
Percentage?
Monocytes, 4-8%