endocrine system Flashcards

1
Q

what is the function of the endocrine system

A

the release and control of the concentration of hormones, the maintenance of the internal environment to maintain homeostasis

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2
Q

is the secretion of most hormones controlled by negative or positive feedback

A

negative

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3
Q

what 3 elements is the endocrine system composed of

A

endocrine cells and glands, hormones, target cells ( cells that will respond to the hormones

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4
Q

where are hormones secreted into by endocrine cells

A

extracellular space

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5
Q

what does anatomically discontinuous mean?

A

it will only take effect when it reaches its target cell, it wont have any effect on the way when in the blood

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6
Q

what inputs do endocrine cells receive

A

neuron, hormone, ion, organic nutrient

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7
Q

how do hormones know they’ve come into contact with a target cell

A

Target cells have receptors for the specific hormone which is why they wont bind to the wrong cell

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8
Q

what are the main types of cell signalling

A

endocrine, neurohormones, panacrine and autocrine, intracrine

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9
Q

how does endocrine hormones signal other hormones

A

via the blood stream to target cells

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10
Q

how do neurocrine hormones send signals to target cells

A

released via synapses and travel via the bloodstream

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11
Q

how do paracrine hormones send signals to target cells

A

they act on adjacent cells

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12
Q

how do autocrine hormones send signals to target cells

A

they act on the cells that secreted them

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13
Q

where is the pineal gland located

A

near the thalamus into the brain

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14
Q

what hormone does the pineal gland produce

A

melatonin

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15
Q

what effect does melatonin have on the body

A

causes the body to feel drowsy and tired, becomes more active in low light intensities

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16
Q

what is the hypothalamus’ role in the endocrine system?

A

regulation of the endocrine organs that are structurally below it

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17
Q

what special cells does the hypothalamus contain

A

neuro-secretory cells (neurons that secrete hormones)

18
Q

what doe the hypothalamus regulate the release of

A

TRH, GHRH, GHIH, GnRH, CRH, oxytocin, ADH

19
Q

what are the two areas of the pituitary gland

A

posterior and anterior

20
Q

what is the function of the posterior pituitary

A

produces oxytocin and anti-diuretic hormone (ADH)

21
Q

what is the function of the anterior pituitary

A

produces thyroid stimulating hormone (TSH), growth hormone (GH)

22
Q

where is the thyroid gland located

A

in the anterior neck

23
Q

what 2 hormones are secreted by the thyroid gland

A

thyroxine (T4) and triiodothyronine (T3)

24
Q

what does the hormones secreted by the thyroid gland do to the body

A

Regulates metabolism, increases protein synthesis, promotes glycolysis/ glucose uptake

25
Q

what is the role of the parathyroid gland

A

regulates the level of calcium in the body by producing parathyroid hormone which increases calcium levels in the blood

26
Q

what hormone is produced by the thymus gland and what is their role in the body

A

thymosins - they help to develop T-Lymphocytes during foetal development in childhood.

27
Q

where is the adrenal medulla located

A

directly above each kidney

28
Q

what does the adrenal medulla secrete

A

catecholamine

29
Q

what effect does the adrenal medulla have on the body

A

fight or flight - increases HR and BP

30
Q

Where is the adrenal cortex located

A

it is the outer few membranes of the adrenal gland which is situated above each kidney

31
Q

what does the adrenal cortex secrete

A

30 different steroid hormones - some of which act as an anti inflammatory agent

32
Q

where is the pancreas located

A

in the folds of the duodenum, located slightly behind the stomach

33
Q

what does the pancreas secrete

A

digestive enzymes such as insulin

34
Q

what is the role of insulin in reducing blood glucose

A

promotes glycogenesis (the break down of glucose to glycogen

35
Q

what are the islets of langerhans

A

They’re a small group of cells that function as an endocrine gland ( contains Alpha, beta and delta cells)

36
Q

what do each type of islets of langerhans secrete

A

alpha- glucagon, beta- insulin, delta- somatostatin

37
Q

what is the role of alpha cells and how does this help control blood glucose levels

A

they release glucagon to control blood glucose levels, the glucagon stimulates the liver to release glucose stores

38
Q

what is the role of beta cells and how does it help control blood glucose levels

A

they release insulin, insulin increases the rate at which glucose is taken up by cells which lowers the blood glucose level,

39
Q

what is the role of delta cells and how does it help control blood glucose levels

A

they produce somatostatin which inhibits both glucagon and insulin

40
Q

how does insulin increases the uptake of glucose

A

when the concentration of glucose is more than normal, insulin binds to an insulin receptor on the surface of the cell causing the glucose channel to open allowing glucose to move into the cell

41
Q

what are the 3 main types of hormones

A

steroids, peptide hormones (insulin glycagon), amino acid derivatives

42
Q
A