endocrine system Flashcards

1
Q

where are hormones produced (2)

A

ductless or endocrine glands

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2
Q

what is method 1 of hormone action

A

when hormones bind to receptors on the cell surface and a second messenger sends the signal into the cell

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3
Q

what is method 2 of hormone action

A

no second messenger is involved. Hormones alter the target cells by activating DNA

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4
Q

what is the function of the hypothalamus in the endocrine system

A

produce hormones (releasing hormones) that stimulate other glands to make hormones

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5
Q

what is the purpose of the pituitary gland

A

produces stimulating hormones which stimulate other glands to make hormones

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6
Q

what is the function of the anterior pituitary

A

receive hormones from the hypothalamus via blood supply

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7
Q

what is the function of the posterior pituitary

A

receive nerve supply from the hypothalamus triggering hormone broduction

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8
Q

what does the posterior pituitary gland produce (2)

A

ADH (anti-diuretic hormone) - involved in water balance.
oxytocin - stimulates labour contractions, promotes a sense of well-being & maternal bonding and behaviour.

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9
Q

what does the anterior pituitary gland produce (2)

A

growth hormone
stimulating hormone

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10
Q

what hormones does the thyroid produce (3)

A

thyroxine (T4) - regulates BMR (basal metabolic rate)
triiodothyronine (T3) - regulates BMR (basal metabolic rate)
calcitonin

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11
Q

what does the parathyroid produce

A

hormones which regulate calcium levels

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12
Q

what does calcitonin regulate

A

how much calcium is deposited the in bone

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13
Q

what happens when thyroxine levels fall (5)

A

The hypothalamus stimulates the pituitary.
The pituitary stimulates TSH (thyroid stimulating hormone.)
The thyroid responds to TSH and secretes thyroxine.
Thyroxine enters the blood and affects the metabolic rate of all cells.
Rising levels of thyroxine stops the brain from producing TSH and the mechanism switches off.

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14
Q

what should the blood glucose levels be before a meal and after

A

before a meal = 4 - 5.9 mmol/L
after a meal = under 7.8 mmol/L

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15
Q

where is glucagon and insulin produced

A

in the pancreatic islets
Glucagon - alpha cells
Insulin - beta cells

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16
Q

how does insulin work

A

binds to receptors on the cell surface and triggers reactions inside the cell. Resulting in glucose transport proteins bringing glucose into the cell.

17
Q

how does glucagon work

A

travels to the liver from the pancreas and converts glycogen into glucose to be released into the bloodstream. switched on during exercise and when hungry and is regulated by the SNS

18
Q

what happens when there is a fall in glucose (4)

A

insulin secretion decreases and glucagon is produced.
less glucose is taken up by cells and respired.
stored glycogen in the liver and muscle is converted into glucose by glycogen.
fatty acids are converted into glucose.

19
Q

what is the difference between type 1 and type 2 diabetes

A

1 - islets are attacked
2 - body is unable to use insulin effectively enough.

20
Q

what happens to the pancreatic islets as we age

A

they produce less insulin.
excess fat and sugar reduces the number of insulin receptors available.

21
Q

what kind of disorder is hyperthyroidism

A

metabolic disorder

22
Q

how is glucose regulated in the bloodstream (5)

A

pancreatic receptors detect glucose rise.
hypothalamus relays information to the pituitary to allow insulin secretion.
insulin converts glucose to glycogen.
The mechanism switches off when high levels of glucose are reached.
Vise versa when glucose levels fall