Endocrine System Flashcards
What system only uses the chemical type of signaling and is usually slow acting, taking care of homeostasis and reproduction?
Endocrine System
What is transported primarily via bloodstream and bind to receptors on target cells? They are also less specific than neural signaling.
Hormones
What are ductless glands whose primary function is to secrete their hormones directly into the surrounding fluid?
Endocrine gland
What system uses glands to release their secretions through ducts (ex. sebaceous and sweat glands)?
Exocrine system
What type of signaling happens when hormones are secreted into the extracellular fluid, diffuse into the body or lymph, and then travel great distances throughout the body?
Endocrine signaling
What type of signaling takes place within the same cell; chemical elicits a respose in the same cell that secreted it (ex. interleukin-1 or IL-1: inflammatory response)?
Autocrine signaling
What is a local intercellular type of communication where a chemical induces a response in neighboring cells?
Paracrine signaling
Enumerate the 5 roles of hormones.
- human reproduction
- growth and development of body tissues (growth spurt)
- metabolism
- fluid and electrolyte balance
- sleep
What are the two major groups of hormones on the basis of chemical structures?
- Amino acids
2. Lipids
What hormones make up the amino acid group?
- Amines
- Peptides
- Proteins
What hormones make up the lipid group?
Steroids
What type of hormone is derived from the modification of single amino acids and is dervied from the amino acids tryptophan or tyrosine?
Amine hormones
Enumerate the organs that compose of the endocrine system.
- Pineal gland
- Thalamus
- Pituitary gland
- Thyroid
- Adrenal glands
- Pancreas
- Uterus
- Ovaries
- Testes
What amino acid is the basis for thyroid hormones, epinephrine, norepinephrine, and dopamine?
Tyrosine
What hormone is secreted by the pineal gland and helps regulate the circadian rhythm?
Melatonin
What hormones are secreted by the adrenal medulla and plays a role in the fight-or-flight response?
Epinephrine and norepinephrine
What are epinephrine and norepinephrine also known as?
Adrenaline and noradrenaline
What hormone is produced in greater quantities in the adrenal medulla (4:1) and is the more powerful hormone over norepinephrine?
Epinephrine
What is the chemical classification of epinephrine and norepinephrine?
Catecholamines
What hormone is secreted by the hypothalamus and inhibits the release of certain anterior pituitary hormones?
Dopamine
What is a protein-based hormone that promotes the growth of body tissues and is produced by the anterior pituitary?
Growth hormone (GH)
What is a peptide-based hormones that promotes milk production and is produced by the anterior pituitary?
Prolactin (PRL)
What is a glycoprotein-based hormone that stimulates thyroid hormone release and is produced in the anterior pituitary?
Thyroid-stimulating hormone (TSH)
What is a peptide-based hormone that stimulates hormone release by the adrenal cortex and is produced by the anterior pituitary?
Adrenocorticotropic hormone (ACTH)
What is a glycoprotein-based hormone that stimulates gamete (or sex cell) production and is produced in the anterior pituitary?
Follicle-stimulating hormone (FSH)
What is a glycoprotein-based hormone that stimulates gamete (or sex cell) production and is produced in the anterior pituitary?
Follicle-stimulating hormone (FSH)
What is a glycoprotein-based hormone that stimulates androgen (male hormone) production by gonads and is produced in the anterior pituitary?
Luteinizing hormone (LH)
What is a glycoprotein-based hormone that stimulates androgen (male hormone) production by gonads and is produced in the anterior pituitary?
Luteinizing hormone (LH)
What is a peptide-based hormone that stimulates water reabsorption by kidneys and is produced by the posterior pituitary?
Antidiuretic hormone (ADH)
What peptide-based hormone stiulates uterine contractions during childbirth and is produced by the posterior pituitary?
Oxytocin
What are two amine-based hormones that stimulate basal metabolic rate (energy used while body is at rest) and are produced in the thyroid?
Thyroxine (T4) and Triiodothyronine (T3)
What is a peptide-based hormone that reduces blood calcium ion levels and is produced in the thyroid?
Calcitonin
What is a peptide-based hormone that increases blood calcium ion levels and is produced in the parathyroid?
Parathyroid hormone (PTH)
What is a steroid-based hormone that increases blood sodium ion levels and is produced in the adrenal cortex? It deals with osmoregulation.
Aldosterone
What steroid-based hormones increase blood glucose levels and are produced in the adrenal cortex? They also deal with metabolism.
Cortisol, corticosterone, cortisone
What amine-based hormones stimulate the fight-or-flight response and are produced in the adrenal medulla?
Epinephrine, norepinephrine
What amine-based hormone regulates sleep cycles and is produced in the pineal gland?
Melatonin
What protein-based hormone reduces blood glucose levels and is produced in the pancreas?
Insulin
What protein-based hormone increases blood glucose levels and is produced in the pancreas?
Glucagon
What steroid-based hormone stimulates the development of male secondary sex characteristics and sperm production and is produced by the testes?
Testosterone
What steroid-based hormones stimulate the development of female secondary sex characteristics and prepare the body for childbirth? They are produced in the ovaries.
Estrogens and progesterone
What type of hormones consist of short chains of amino acids (ex. antidiuretic hormone or ADH)?
Peptide hormones
What type of peptide hormone is produced by the heart and helps to decrease blood pressure?
Atrial-natriuretic peptide
What type of hormones are made of longer polypeptides (ex. growth hormone)?
Protein hormones
What type of hormones are derived from lipid cholesterol (ex. testosterone and estrogens)? They are not soluble in water (hydrophobic).
Steroid hormones
What refers to the time required for half the concentration of the hormone to be degraded?
Half-life
What must steriod hormones do to arrive at their target cell?
Because blood is water-based, steriod hormones must travel to their target cell bound to a transport protein.
List the pathways of hormone action.
Hormone - hormone receptor - process the message - initiating other signaling events or cellular mechanisms - target cell’s response
What is the “command center” of the endocrine system? It coordinates the messages of the endocrine and nervous systems.
Hypothalamus-pituitary complex
What part of the brain is located in the diencephalon, located anterior and inferior to the thalamus, and has both neural and endocrine functions? It is a bean-sized organ.
Hypothalamus
What gland is cradled within the sella turcica of the sphenoid bone and consists of a posterior and anterior lobe?
Pituitary gland
What is another name for the posterior pituitary? It is a neural tissue.
Neurohypophysis
What is another name for the anterior pituitary? It is a glandular tissue that develops from the primitive digestive tract.
Adenohypophysis
Explain what oxytocin does during pregnancy.
- stimulates uterine contractions
- dilates the cervix
- toward the end of pregnancy, oxytocin receptors in the uterus increases and the smooth muscles of the uterus become more sensitive to its effects.
- Cervical stretching signals for additional oxytocin from the hypothalamus and the pituitary gland releases it.
What type of feedback mechanism happens when oxytocin is released?
Positive feedback mechanism
What hormone is necessary for the milk ejection reflex (“let-down”) in breastfeeding, contributes to parent-newborn bonding known as attachement, and is involved in feelings of love and closeness as well as sexual response?
Oxytocin
Explain the milk let down reflex.
newborn begins suckling - sensory receptors in nipples - hypothalamus - oxytocin is secreted and released into the bloodstream - cells in the mother’s milk ducts contract - ejects milk into the infant’s mouth
What is another name for the antidiuretic hormone (ADH)?
Vasopressin
What is the name of specialized cells within the hypothalamus that are sensitive to the concentration of sodium ions and other solutes in the blood?
Osmoreceptors
What are the target cells of the antidiuretic hormone (ADH)?
Tubular cells of the kidneys
What type of feedback loop does ADH trigger?
Negative feedback loop
What are some conditions that present high blood osmolarity?
- During dehydration
2. Following a very salty meal
What refer to the concentration of dissolved particles of chemicals and minerals - such as sodium and other electrolytes - in your serum? A higher concentration means you have more particles in your serum while a lower concentraton means the particles are more diluted.
Blood osmolality
What are the effects of the antidiuretic hormone (ADH) or vasopressin?
- incease epithelial permeability of tubular kidney cells to water
- Increase water reabsorption in body
- Increase blood pressure by constricting blood vessels