Endocrine II Flashcards

1
Q

glands are composed mostly of what kind of cells?

A

secreting epithelial cells

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2
Q

what cell is the most common type to form cancer

A

epithelial cells with their ability to easily undergo mitosis

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3
Q

what interacts with and copntrols most secretory activites of the pituitary

A

they hypothalamus of the brain

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4
Q

the two functionaly different areas of the pituitary

A

anterior

posterior

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5
Q

posterior pituitary functions

A

a storage are for neurohormones produced by neurons whose bodies are in the hypothalamus but whose axons extend into the posterior pituitary
the neurohormones are then picked up by the blood

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6
Q

anterior pituitary functions

A

has no direct nervous connection to the hypothalamus but is signaled into action when hypothalamic neurohormones are secreted and carried to the anterior pituitary epithelial cells via a specialized cirulatoryu route.

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7
Q

how many anterior pituitary hormones may be secreted

A

6

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8
Q

hypothalamus hormones

A

GHRH - growth hormone releasing hormone
TRH - thyrotropin releasing hormone
GnRH - gonadotropin releasing hormone

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9
Q

hypothalamus targets what cells

A

the anterior pituitary, which in turn makes

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10
Q

anterior pituitary hormones

A
GH - growth hormone
TSH - thyroid stimulating hormone
FSH - follicle-stimulating hormone
LH - luteinizing hormone
prolactin
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11
Q

GH

A

growth hormone

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12
Q

what does GH target

A

connective tissue

bones

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13
Q

the action of GH

A

bone growing

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14
Q

imbalances of GH

A

too little in infancy results in pituitary dwarfism

too much in childhood results in gigantism

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15
Q

acromegaly

A

once growth plates close, past the point of normal

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16
Q

TSH

A

thyroid stimulating hormone

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17
Q

what does TSH target

A

thyroid gland

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18
Q

the action of TSH

A

stimulates thyroid glands to release thyroid hromones

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19
Q

an imbalance of TSH

A

graves disease

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20
Q

graves disease

A

an autoimmune immunoglobulin imitates normal TSH and causes an overstimulation of the thyroid gland and hypersecretion of thyroid hormones

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21
Q

what does prolactin target

A

cells of mammary glands that produce milk

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22
Q

actions of prolactin

A

promotes lactation

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23
Q

imbalance of prolactin

A

innapropriate milk production

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24
Q

LH and FSH

A

leutinizing hormone and follicle-stimulating hormone

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25
what does LH and FSH target
active in the produiction of sperm in males, oocytes in females and reproductive hormones in both sexes
26
where are cell bodies of posterior pituitary
cells bodies are in hypothalamus & axons are with hormone secretion are in posterior pituitary
27
posterior pituitary hormones
oxytocin | ADH
28
what does oxytocin target
uterine cells
29
action of oxytocin
to contract uterus
30
imbalance of oxytocin
synthetic oxytocin can be given to induce labor
31
ADH
antidiuretic hormone
32
what does ADH target
kidney cells
33
actions of ADH
forces cells to reabsorb more water, regulates osmosis
34
imbalance of ADH
diabetes insipidus
35
thyroid hormones
TH - thyroid hormones | T3 & T4
36
T3 & T4
thyroxine
37
target of TH
all over body
38
actions of TH
increases cell metabolism
39
imbalance of TH
hyperthyroidism Hypothyroidism goiter graves disease
40
goiter
iodine deficiency goiter, cells undergo unusual amount of mitosis
41
parathyroid hormones
PTH - patathyroid hormone
42
the target of PTH
skeleton kidneys intestine
43
actions of PTH
controlls the calcium levels in the blood | increases blood Ca++
44
what does PTH stimulate
osteoclasts kidney tubules intestinal cells
45
adrenal gland hormones
aldosterone cortisol androgens epinephrine, norepinephrine
46
what does aldosterone target
kidney tubules cells
47
action of aldosterone
attracts Na+ and reabsorption | water follows, increase blood volume
48
target of cortisol (glucocorticoids)
body cells
49
action of cortisol
important for stopping inflammation
50
imbalance of cortisol
increase - kushings disease | decrease - addisons disease
51
androgens
male type sex hormones converted to testosterone in males and estrogens in females.
52
what are androgens responsible for
for axillary & pubic hair in females. available first during fetal development
53
epinephrine, norepinephrine targets
heart and skeletal muscles | parasympathetic and sympathetic responses
54
thymus hormones
thymosin
55
what does thymosin target
white blood cells
56
imbalance of thymus
hypo causes incomplete immune protection lacking T-cell development
57
gonads
ovaries | testes
58
ovaries hormones
estrogen and progesterone
59
testes
testerone
60
pancreas
insulin | glucagon
61
insulin
b-cells respond to increase blood glucose
62
insulin targets what
tissue cells | liver cells
63
action of insulin
uptake of glucose for utlization and fat formation | link glucose into long glycogen molecules
64
imbalance of insulin
hyposecretion - type 1 diabetes
65
glucagon
a-cell respond to decrease blood surgar
66
target of glucagon
liver cells
67
action of glucagon
break apart glycogen and release glucose molecules | synthesis of new glucose from other body sources
68
endocrine glands
``` hypothalamus anterior pituitary posterior pituitary thyroid parathyroid adrenal thymus gonads pancreas ```