cardiovascular blood II Flashcards
normal count for leukocytes
5,000-10,000 cells
leukocytosis
rapidly increasing blood cells
leukemia
cancer of a population of wbcs
leukopenia
from drugs, anti-cancer therapy
how to wbcs move around
ameboid movement
chemotaxis
pus
diapedesis
leaving blood vessels
chemotaxis
chemical attraction
types of white blood cells
granulocytes
agranulocytes
platelets
granulocytes
neutrophils
eosinophil
basophil
neutrophils
50-70%
numbers rise in actue bacterial infection
active migrating phagocytes, attracted by inflammation
larged with lobed nuclei
eosinophil
2-4%
large red granules
attracted to areas of inflammation and allergic response
increase in mucous secretions from allergies
basophils
<1%
large purple granules
attracted to areas of injury and inflammation and release histamine causing increased vessel permeability
agranulocytes
lymphocytes
monocytes
lymphocytes
25-45%
rise in viral infection
small with large nucleus
T-cells & B-Cells
t-cells
act as messengers to other wbcs or attack foreign invaders directly
b-cells
antibody production
monocytes
3-8%
big single nucleus U-shaped
macrophages
platelets
small fragments of a much large blood cell release from the marrow
function of platelets
used in blood clotting
life span of platelets
5-10 days
shortage of platelets
thrombocytopenia
numerous small localized hemorrhages
petechiae
hemostasis and how the body stops bleeding
vessel spasm
platelt plug forms
coagulation
how does a platelet plug form
platelts get sticky from contact with disrupted cells
fibrinogen protein joins platelts together (aggregation) to form plug
steps of coagulation
soluble fibrinogen changes to insoluble fibrin threads
necessary for clot formation
fibrinogen
platelets
vit K, Ca++ and substances called clotting factors
what are children given to ensure clotting during surgery
vit. k injections
fibrinolysis
breaking down established clots
what is t-pa
a clot buster given is unwanted clot is suspected as in a stroke
what are anticoagulants
prevent clot formation
medications that are anticoagulants
heparin
coumadin
aspirin
what happens when EDTA is in a tube when blood is drawn
blood does not clot. the liquid portion is plasma
clotting disorders
hemophilia
thrombus
embolus
DVT
hemophilia
genetically incorrect or missing clotting factors
thrombus
blood clot attached to vessel wall. may grow and form plaque in arteries
embolus
floating blood clot. when it sticks in a vessel, tissue dies from hypoxia creating an embolism
collection of blood for analysis
venipuncture
fingerstick
arterial stick - for anaylsis of blood gases
what they look for in blood
red cell count hemoglobin hematocrit wbc count differential white count clotting blood chemistry
anemia ranges
rbc < 37% for males
polycythemia
rbcs>55-80%
overproduction of EPO
very thick blood
figuring out hb and hct
hb is 1/3 of hct
ex female 12gms hb = 36 hct
range for wbc
5,000-10,000