endocrine histology Flashcards

1
Q

what connects pituitary gland to hypothalamus

A

infundibulum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is proper name for ant. pituitary

A

adenohypophysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

3 types of cell in adenohypophyissi histology

A

chromophobes 50%
acidophils 40%
basophils 10%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are Herring bodies

A

axon bulgings, containing secretory granules, spheroid, eosinophilic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is name for post. pituitary

A

neurohypophysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

adenoma histology in pituitary

A

monotonous pattern, uniform cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most comon adenomas in anterior pituitary

A

lactotroph amd somatotroph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which cells produce parathyroid hormone

A

chief

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

functional unit of the thyroid

A

follicle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what cells are in between thyroid follices

A

C (clear) cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is in colloid

A

iodinated thyroglubulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is t4

A

thyroxine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what do Clear cells secrete

A

calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

normal morphology of thyroid follicular epithelial cells

A

cuboidal or low columnar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Graves disease histology

A

Diffuse hypertrophy and hyperplasia of follicular cells (tall and columnar and more crowded) —results in papillary formation which project into the lumen.

Lymphoid infiltration (mostly T cells) into the thyroid stroma

Cells often are enlarged and can show cytoplasmic eosinophilia, with enlarged nuclei and can mimic the nuclei of papillary thyroid carcinoma (no fibrovascular cores)

The colloid shows scalloping reflecting increased use of the colloid to produce thyroxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

hashimoto antigen against

A

follicular cells

17
Q

moprhology of hashimoto

A

eosinophilic epithelial Hurthle cells (big, granular, oncocytes) and fibrotic bands.

18
Q

goitre?

A

graves
Hashimoto BUT eventually atrophy

19
Q
A

scalloping Graves disease, colloid is atrophied

20
Q

which is widest zona in adrenal gland

A

fasciculat

21
Q
A
22
Q

chromaffin cells are called becuase

A

stain with chromium

23
Q

origin of chromaffin cells

A

neurones

24
Q

where are chromaffin cells

A

adrenal medulla

25
Q

chromaffin cells produce

A

adrenaline

26
Q

functional adenomas in adrenal cortex cause

A

Cushings

27
Q

stimulants (2) of ZG

A

K levels and angiotensin 2

28
Q

difference between Cushings syndrom and disease

A

???

29
Q

ZF cells are filled with

A

lipid droplets

30
Q

what is addisons disease

A

autoimmune
adrenal hypofunction
degeneration of the cortex

31
Q

histopathology of addisons

A

Atrophic glands

Fibrosis of adrenal capsule

No differentiation of the cortical epithelial areas and the medulla (below)

Marked lymphocytic infiltration (autoimmune)

32
Q

pheocromocytoma means

A

dark colour tumour

33
Q

pheochromocytoma location

A

medulla

34
Q

Symptoms of hyperthyroidism

A

High blood pressure, Headache, Heavy sweating, Rapid heartbeat, Tremors
Pallor, Shortness of breath
Panic attack-type symptoms

35
Q

exocrine pancreas produces

A

digestive enzyems

36
Q

endocrine pancreas prodyces

A

insulin
glucagon
pancreatic polypeptides

37
Q

histopathology DMt1

A

shrunken and fewer islets

38
Q

DT2 what can you see

A

amyloid deposits

39
Q
A