Endocrine drugs 4: Hypothalamic and Pituitary

Question 1

androgen receptor antagonists

Answer 1

flutamide
bicalutamide
nilutamide

Question 2

erythromelalgia

Answer 2

bromocriptine, pergolide, cabergoline

Question 3

GH agonists

Answer 3

somatropin (recombinant GH)

mecasermin (recombinant IGF-1)

Question 4

GH antagonist

Answer 4

octreotide

pegvisomant

Question 5

mixed lh and fsh agonist

Answer 5

menotropin

Question 6

oxytocin antagonist

Answer 6

atosiban

Question 7

vasopressin antagonist

Answer 7

conivaptan

Question 8

mecasermin

Answer 8

GH agonist

Recombinant IGF-1

Question 9

ganirelix

Answer 9

gnrh antagonist

Question 10

leuprolide

Answer 10

gnrh agonist

Question 11

atosiban

Answer 11

oxytocin antagonist

Question 12

conivaptan

Answer 12

vasopressin antagonist

Question 13

peripheral oxytocin receptor agonist

Answer 13

carbetocin

Question 14

adh antagonist that’s more selective to V2 receptors

Answer 14

tolvaptan

Question 15

S/E: slipped capital femoral epiphysis

Answer 15

somatropin

-other s/e: intracranial hypertension, pseudotumor cerebri

Question 16

remarks on pegvisomant

Answer 16

GH receptor antagonist

USES
-acromegaly

Question 17

GnRH antagonists

Answer 17

DEGARELIX
-used for prostate CA

GANIRELIX
-used to prevent LH surge in controlled ovulation