Endocrine COPY

Question 1

What kind of drug can you give to someone who has gigantism?

Answer 1

Somatostatin
sandostatin
sandovert

these are hypothalamic releasing hormones
gonandotropin releasing hormone

Question 2

route chemical castration given

Answer 2

Injection only

Question 3

somatostatin analog

Answer 3

Octreoid (Sandostatin)

gonandotropin releasing hormone

Question 4

Somavert Contraindications

Answer 4

obesity

respiratory impairment

Question 5

SE of corticosteriods

Answer 5

edema
peptic ulcers
delayed wound healing
infections
osteoporosis

Question 6

CI for steriod use

Answer 6

these are drugs that end in -ONE

viral and fungal infections because its supressing the immune system

Question 7

example of a mineralcorticoid

Answer 7

aldosterone

Question 8

drugs that enhances corticosteriods

Answer 8

(lack of androgen)
estrogen
Birth control pills

(lack of cortisol)
ketoconazole (immune response)
macrolide ABX

(improve GI distress)
diuretics

Question 9

decrease the effects of corticosteriods

Answer 9

Antacids
cholestyramine
carbazepine (anticonvulsant mood stabilizer)
phenytoin (seizure, their CNS is already altered)
Rifampin

Question 10

myxedema

is seen in which dx?

Answer 10

facial swelling, peiorbital edema, cheek edema tounge swollen

hypothyroidism

Question 11

late clinical manifestations of HypOthyroidism

Answer 11

subnormal temp
weight gain
bradycardia
decreased LOC
thickened skin
cardiac complications

Question 12

how is Synthroid dosed?

Answer 12

mcg

Question 13

Synthroid

Answer 13

long half life

takes time to work- 3 months and have dose readjusted

Question 14

t4 replacement

Answer 14

synthroid

Question 15

synthroid pt education

Answer 15

take in morning
take with food

no grapefruit
no antacids
no iron supplements

stick with one brand
pregnancy risk category A

Question 16

how does levothroxine (synthroid) affect warfarin

Answer 16

enhance

Question 17

how does levothroxine (synthroid) affect catecholamines

Answer 17

enhanced

Question 18

how does levothroxine (synthroid) affect digoxin

Answer 18

diminished/reduces

Question 19

how does levothroxine (synthroid) affect insulin

Answer 19

reduces

synthroid will increase metabolic rate, increaing the amount of glucose molecules, reducing the efficency of insulin

Question 20

drugs that increase effects of synthroid

Answer 20

Antidepressants
adrenergic antiasthmatic drugs
nasal decongestants

Question 21

first signs of hyperthyroidism

Answer 21

jitteriness
tachycardia
insomnia
HTN

Question 22

medications that affect thyroid function

Answer 22

antivirals in heptatis C

cardiac drug aminodarone

Question 23

if synthroid dose is too low, what are the symptoms we can expect

Answer 23

bradycardia
lethargy
constipation
excessive fatigue
excessive sleeping

Question 24

If synthroid dose is too high watch for

Answer 24

irritatibility
palpitations
tachycardia
dairrhea
tremors
insomnia

Question 25

thyroid storm

Answer 25

hypertensive tachycardic bulging eyes

Question 26

hyperthyroid drugs inhibits release of thyroid hormone visual

Answer 26

SSKI: saturated solution of KI Lugols solution Propanolol (inderal) - also a beta blocker (chills them out)

Question 27

biphosphonate SE

Answer 27

GI ulcerations stomach acid osteonecrosis of the jaw and hip bones

Question 28

when giving GH exogenously what are some nursing considerations?

Answer 28

watch the blood sugar- hyperglycemia

Question 29

what posterior pituitary hormone medication can I used for GI bleeding?

Answer 29

pitressin- a synthetic ADH

Question 30

nursing consideration when using Evista*

Answer 30

no pain killers needed | estrogen also reduces pain

Question 31

SE of SERMS (evista)

Answer 31

increased risk of GYN cancer

Question 32

CI for monoclonal antibody use (denosumab)

Answer 32

immunosupressed

Question 33

Which is the only drug for osteoporosis that increases bone formation? SE?

Answer 33

Teriparatide (Forteo) which is Parathyroid hormone SE: osteosarcoma think: forteo is fortified

Question 34

Patient teaching with osteoporosis

Answer 34

500 mg Calcium 2x a day antacids w/ calcium ``` take these meds 2 hours apart: iron tetracycline ciprofloxacin phenytoin ```

Question 35

Patient teaching: biphosphonates

Answer 35

6-8 oz water 30 min before food, fluid or other medciation dont take calcium within 2 hours of biphosphonates take meds in an upright position and do not lay down for 30 min (causes you to have gastric irritation form increased HCl report new or worsening esophageal irritation

Question 36

___ potentiates/increases power of digoxin, can be given in cardiac emergencies and situations

Answer 36

calcium supplement

Question 37

What drugs regulate calcium and bone metabolism

Answer 37

``` lasix- helps void out calcium phosphate salts- replace calcium IVF normal saline- flush out calcium corticosteriods steriods ```

Question 38

how does phosphate salts regulate calcium and bone metabolism

Answer 38

calcium replaces

Question 39

Hormone replacement therpay risk***

Answer 39

increases risk of endometrial and ovarian cancer

Question 40

Drugs that reduce effectivness of estrogen

Answer 40

really smelly and rotten rifampin st johns wort antiepileptic agents ritonavir

Question 41

Drugs whose effects are decreased by estrogens

Answer 41

Warfarin | insulin

Question 42

Drugs whose effects are increased by estrogens

Answer 42

those dudes cant trick Theophylline diazepam chlordiazepoxide tricyclic antidepressants

Question 43

ACTH stimulates production of | released from

Answer 43

corticosteriods in the adrenal cortex | anterior pituitary

Question 44

GH stimulates

Answer 44

body cells | released from anterior pituitary

Question 45

corticotropin stimulates | released from

Answer 45

adrenal cortex