Endocrine COPY Flashcards

1
Q

What kind of drug can you give to someone who has gigantism?

A

Somatostatin
sandostatin
sandovert

these are hypothalamic releasing hormones
gonandotropin releasing hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

route chemical castration given

A

Injection only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

somatostatin analog

A

Octreoid (Sandostatin)

gonandotropin releasing hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Somavert Contraindications

A

obesity

respiratory impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SE of corticosteriods

A
edema
peptic ulcers
delayed wound healing
infections
osteoporosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CI for steriod use

A

these are drugs that end in -ONE

viral and fungal infections because its supressing the immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

example of a mineralcorticoid

A

aldosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

drugs that enhances corticosteriods

A

(lack of androgen)
estrogen
Birth control pills

(lack of cortisol)
ketoconazole (immune response)
macrolide ABX

(improve GI distress)
diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

decrease the effects of corticosteriods

A

Antacids
cholestyramine
carbazepine (anticonvulsant mood stabilizer)
phenytoin (seizure, their CNS is already altered)
Rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

myxedema

is seen in which dx?

A

facial swelling, peiorbital edema, cheek edema tounge swollen

hypothyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

late clinical manifestations of HypOthyroidism

A
subnormal temp
weight gain
bradycardia
decreased LOC
thickened skin
cardiac complications
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how is Synthroid dosed?

A

mcg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Synthroid

A

long half life

takes time to work- 3 months and have dose readjusted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

t4 replacement

A

synthroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

synthroid pt education

A

take in morning
take with food

no grapefruit
no antacids
no iron supplements

stick with one brand
pregnancy risk category A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how does levothroxine (synthroid) affect warfarin

A

enhance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how does levothroxine (synthroid) affect catecholamines

A

enhanced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

how does levothroxine (synthroid) affect digoxin

A

diminished/reduces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

how does levothroxine (synthroid) affect insulin

A

reduces

synthroid will increase metabolic rate, increaing the amount of glucose molecules, reducing the efficency of insulin

20
Q

drugs that increase effects of synthroid

A

Antidepressants
adrenergic antiasthmatic drugs
nasal decongestants

21
Q

first signs of hyperthyroidism

A

jitteriness
tachycardia
insomnia
HTN

22
Q

medications that affect thyroid function

A

antivirals in heptatis C

cardiac drug aminodarone

23
Q

if synthroid dose is too low, what are the symptoms we can expect

A
bradycardia
lethargy
constipation
excessive fatigue
excessive sleeping
24
Q

If synthroid dose is too high watch for

A
irritatibility
palpitations
tachycardia
dairrhea
tremors
insomnia
25
Q

thyroid storm

A

hypertensive
tachycardic
bulging eyes

26
Q

hyperthyroid drugs
inhibits release of thyroid hormone

visual

A

SSKI: saturated solution of KI
Lugols solution
Propanolol (inderal) - also a beta blocker (chills them out)

27
Q

biphosphonate SE

A

GI ulcerations
stomach acid
osteonecrosis of the jaw and hip bones

28
Q

when giving GH exogenously what are some nursing considerations?

A

watch the blood sugar- hyperglycemia

29
Q

what posterior pituitary hormone medication can I used for GI bleeding?

A

pitressin- a synthetic ADH

30
Q

nursing consideration when using Evista*

A

no pain killers needed

estrogen also reduces pain

31
Q

SE of SERMS (evista)

A

increased risk of GYN cancer

32
Q

CI for monoclonal antibody use (denosumab)

A

immunosupressed

33
Q

Which is the only drug for osteoporosis that increases bone formation?

SE?

A

Teriparatide (Forteo) which is Parathyroid hormone

SE: osteosarcoma

think: forteo is fortified

34
Q

Patient teaching with osteoporosis

A

500 mg Calcium 2x a day
antacids w/ calcium

take these meds 2 hours apart: 
iron
tetracycline
ciprofloxacin
phenytoin
35
Q

Patient teaching: biphosphonates

A

6-8 oz water 30 min before food, fluid or other medciation

dont take calcium within 2 hours of biphosphonates

take meds in an upright position and do not lay down for 30 min (causes you to have gastric irritation form increased HCl
report new or worsening esophageal irritation

36
Q

___ potentiates/increases power of digoxin, can be given in cardiac emergencies and situations

A

calcium supplement

37
Q

What drugs regulate calcium and bone metabolism

A
lasix- helps void out calcium
phosphate salts- replace calcium
IVF normal saline- flush out calcium
corticosteriods
steriods
38
Q

how does phosphate salts regulate calcium and bone metabolism

A

calcium replaces

39
Q

Hormone replacement therpay risk***

A

increases risk of endometrial and ovarian cancer

40
Q

Drugs that reduce effectivness of estrogen

A

really smelly and rotten

rifampin
st johns wort
antiepileptic agents
ritonavir

41
Q

Drugs whose effects are decreased by estrogens

A

Warfarin

insulin

42
Q

Drugs whose effects are increased by estrogens

A

those dudes cant trick

Theophylline
diazepam
chlordiazepoxide
tricyclic antidepressants

43
Q

ACTH stimulates production of

released from

A

corticosteriods in the adrenal cortex

anterior pituitary

44
Q

GH stimulates

A

body cells

released from anterior pituitary

45
Q

corticotropin stimulates

released from

A

adrenal cortex