Diabetes/Insulin COPY

Question 1

what do Sulfonylureas do?

SE?

Answer 1

increase secretion of insulin
(can only be effective if theres functioning beta cells)

pt education: monitor for s/s for hypoglycemia

think: since ur increasing insulin production

Question 2

alpha-glucosidase inhibitor action

Answer 2

delay glucose absorption in GI tract causing smaller increase post prandially (

Question 3

anti-hyperglycemic drug, why?

type?

Answer 3

metformin- b/c it increases glucose use by muscle and fat cells

type: biguanide

Question 4

SE of glitzaones (thiazolidinediones)**

Answer 4

risk of CHF and edema

hint: its not all glitzy glam if it can give u CHF and edema

Question 5

CI for meglitinides

Answer 5

skip dose if u skip meal

Question 6

which drug can i use that causes the growth of beta cells?

type

Answer 6

Sitagliptin (Januvia)

dipeptidyl peptidase-4 (DPP-4 Inhibitors)

Question 7

which is the drug that causes you to urinate blood glucose?

type?

Answer 7

Empagliflozin (Jardiance)
Canaglifozin (invokana)
Dapagliflozin (Farxiga)

hint: it will be out in a jiffy, jif

sodium glucose transporter 2 inhibitor

Question 8

which drug activates dopamine receptors in the CNS?

Answer 8

Bromocriptine (Clycoset)

neurotransmitter manipulation- IN BRAIN to control blood glucose

Question 9

How often is eventide (byetta) given

type?

Answer 9

daily

incretin hormone- 2B’s

Question 10

How often is Exematide ER (bydureon) given

type?

Answer 10

once a week

subQ

Question 11

amylin analog drug is called

SE

Answer 11

Pramlintide (symlin)

nausea
sensation of fullness
hypoglycemia

Reminder: amylin decreases blood sugar

Question 12

route Pramlintide (Symlin) is injected***

Answer 12

subcutaneous injection

do not mix in the same syringe with insulin

Question 13

What type of medical condition can use an amylin analog?

Answer 13

type II diabetics

Question 14

type II diabetic with needle eversion can use

Answer 14

Pramlintide (symlin)
afreeza
insulin pump

Question 15

which are the GLPs that are taken daily

Answer 15

Victoza (liraglutide)

Adlyxin (lixisenatide)

Question 16

Which are the types of GLPs need to be taken weekly

Answer 16

Trulicity (Dulaglutide)
Tanzeum (albiglutide)
ozempic (semaglutide)

Question 17

SE of GLP’s

Answer 17

hypoglycemia, weight loss

Question 18

Xultopgy (IDeglira) is a combination ____(drug type), composed of ___ and ____

Answer 18

GLP

Tresiba
Victoza (liraglutide)

Question 19

Soliqua (Lixilan) is a combination drug ____ (drug type), composed of ___ and ____

Answer 19

Lantus (insulin glargine)
Adlyxin (lixisenatide)

(Hint: Lauras initials)

Question 20

Causes hyperglycemia

Answer 20

Bee pollen
Gingo biloba
glucosamine (impaired beta cell function)

Question 21

How can we treat DKA?

Answer 21

NS for dehydration**

insulin IV drip

Question 22

post up patient meds

Answer 22

insulin with IV dextrose

Question 23

how is glucose gel administered?

Answer 23

buccal

Question 24

pt education for sulfonylureas

Answer 24

pt education: monitor for s/s for hypoglycemia

Question 25

which type of diabetic can use sulfonylureas

Answer 25

type 2- can only work if person has functioning beta cells

Question 26

metformin (type?) | CI?

Answer 26

``` fever sepsis trauma major surgery acidosis hepatic/renal dx CV ot respiratory insufficency hypoxia lactic acidosis ```

Question 27

how often is metformin given

Answer 27

1-2 times a day

Question 28

Januvia type | action

Answer 28

blocks an enzyme that degrades insulin | beta cell neogenesis

Question 29

CI for DD4 drug? | example of drug

Answer 29

Januvia | cannot take with exogenous insulin

Question 30

CI of sodium glucose cotransporter 2 inhibitor

Answer 30

hypoglycemia | DKA- monitor carefully!

Question 31

Dopamine Receptor Agonist- name of drug? CI?

Answer 31

Bromocriptine (Clycoset) taper* *Do not use with ergot drugs

Question 32

Dopamine Receptor Agonist- name of drug? SE?

Answer 32

Bromocriptine (Clycoset) Decreases fatty acids, Decreased bp dec triglycerides dizziness GI symptoms

Question 33

"natural helper hormone"

Answer 33

``` Exenatide (Byetta) Exematide ER (Bydureon) ``` stimulates correct amount of insulin production in pancreas

Question 34

stimulates insulin release

Answer 34

GLP receptor agonist

Question 35

risk of GLP's

Answer 35

Thyroid CA, pancreatitis

Question 36

causes hypoglycemia

Answer 36

``` basil bay leaf cinnamon chromium echinacea garlic ginseng glucomannan guar gum ```