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Pharm Exam 1 and Exam 2 final > AntiCoags > Flashcards

AntiCoags Flashcards

1
Q

INR normal value

A

1, if on anticoagulant number will be higher

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2
Q

PT (prothrombin time)

A

9.5-12 s

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3
Q

PTT (partial thromboplastic time)

A

60-70s intrinsic pathway

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4
Q

if we get an INR value of 3, we would:
administer dose
hold dose

A

hold dose- let it get metabolized and recheck INR

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5
Q

who receives a d’dimer and bleeding time test

A

pt receiving thrombolytics

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6
Q

types of heparin

A

Dalteparin (fragmin)

Enoxaprina (lovenox)

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7
Q

Drug class: heparin action?

A

prevention of further thrombi/thrombi extension

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8
Q

contraindications for heparin

A

bleeders

GI bleeders, hemmoragic stroke, coagulapathies etc

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9
Q

You receive a new order for an anticoag, what is your first concern?

A

get coag’s for a baseline.

monitor coag’s 4 hours after treatement.

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10
Q

if the INR is close to normal levels prescriber will most likely

A

increase the dose

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11
Q

anticoagulant that requires frequent adjustments, making adhearance troublesome!

A

coumadin

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12
Q

Which drug class is a DVT prophylaxis and prevent stroke in afib

What drugs belong to this class

A

Direct factor Xa Inhibitor

Eliquis
Xarelto

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13
Q

pradaxa antidote

what kind of drug is pradaxa?

A

praxbind

these drugs are Direct thrombin inhibitor (DTI’s)

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14
Q

asa and nsaids action

A

inhibit prostaglandin synthesis

inhibit aggregations of platelets

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15
Q

if you mix ASA with persantin =

A

aggrenox

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16
Q

types of antiplatelet meds

A

Asprin ASA
NSAIDS
(dipyridamole) persantin
aggrenox

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17
Q

platelet reducing drug

what is it used for?

A

agrylin

used for pts with thrombocytopenia, NOT CARDIAC pts

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18
Q

activating factor 10A inhibitors, names of drugs and routes

A

Fondaparinux (Arixtra)- parental

Edoxaban (Savaysa)- route SO AP!

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19
Q

PAR-1 drug called

A

zontivity

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20
Q

what does agrylin do?

A

reducing production of platlets in the bone marrow

NOT keeping the platelets from aggregating

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21
Q

What is the drug of choice to prevent thrombosis in stented cardiac vessels?

A

ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS P2Y

22
Q

What are the types of ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS

A

Clopidogrel (Plavix)
Ticlopidine (Ticlid) (TIA’s)
Ticagrelor (Brilinta)
Prasugrel (Effient)

23
Q

drug that treats acute coronary syndrome

A

Ticagrelor (Brilinta)

24
Q

Adenosince diphosphate receptor antagonist P2Y drug thats “more effective than Plavix”

A

Ticagrelor (Brilinta)

25
Q

what drug do we use to prevent clots in stented patients?

A

P2Y

26
Q

given as quick IV bolus at time of an MI

A

integrelin**

27
Q

anticoag given for intermittent claudication

definition

A

pain in calves

Cilostazol (Pletal)

28
Q

what route is integrilin given during MI

A

IV bolus

29
Q

PT/PTT values under therapy

A

1.5-2 times control

30
Q

A patient being treated with coumadin, what lab values do we look at

A

PT

INR

31
Q

A patient taking Heparin we are looking at what lab values

A

PTT

APTT use the picture slide on S23 (2 T’s)

32
Q

those with CVD or risk of should have s. cholesterol at

what is the optimal goal level

A

<100

less than 70

33
Q

what age group is placed on statin?

A

40-75

34
Q

those with ___ conditions should be placed on statins even if their cholesterol is normal

A 
MI
CVD
TIA
PAD
angina
35
Q

Dyslipidemic medication that is a bile acid sequestrant

A

Colesevelam (Welchol)

36
Q

Nursing precaution with statin

A

Hard on liver: monitor LFT’s 6 and 12 weeks

Grapefruit juice increases drug levels

37
Q

SE of statin

A

watch for muscle pain and weakness
rhabdomylosis - myopathy
gallstones

38
Q

contraindications of statin

A

liver disease

39
Q

when should a statin be administered?

why?

A

hour of sleep or evening meal

cholesterol is produced at night
liver is sleeping at night, less SE

40
Q

Which statin needs a lower dose in asians?

A

Rosuvastatin (Crestor)

41
Q

What type of statin treats hypertiglyceridemia?

route?

A

MTP inhibitor such as Lomitapid (Juxtapid)
(i and i= i in hypertriglyceridiemia and juxapid)
oral

42
Q

SE of MTP inhibitor

A

GI upset

43
Q

What do PCSK9 inhibitors do?

A

block protein that enter LDL receptors (in liver), which allow for the transport of LDL into the cell for metabolism

44
Q

name of a PCSK9 drug

how often is it utilized?

A

Praluent (alirocumab)

an antibody- 2x a month

45
Q

What is the risk of taking Fibrates?

what kind of drug are they?

A

Receptor drug

increased risk of rhabdomyolysis when taking with statins

increased risk of bleeding when taking with coumadin

46
Q

What type of nursing education would a person taking Zetia need?

A

greasy poop

47
Q

Niacin nicotinic acid SE

A 
heptatoxic
flushing
intolerance of heat
redness
sweating of the face
48
Q

treatment for sinus bradycardia

what type of drug is this?

what is the action of this drug?

When is this drug used?

A

atropine

anticholinergic drug

slows the HR

When patient shows signs of low perfusion- tired, weak dizzy passing out. If asymptomatic DO NOT TREAT

49
Q

Quinidex Contraindications

What type of drug is this?

A

HF

sodium channel blocker

50
Q

Quinidex action

A

widens QRS

prolongs QT interval

51
Q

Quinidex SE

A

fatal dysrthmias

52
Q

vitamin K is an antidote for

what is the other names for is

A

Coumoudin

Aqua and phytonadione

Pharm Exam 1 and Exam 2 final (18 decks)

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