Endocrine (5) Flashcards
Hyptothalamus –> Anterior Pitutiary
Gonadotropin-releasing horomones (GnRH) –> FSH and LH
Growth hormone-releasing hormone (GHRH) –> Growth Hormone (GH)
Thyroid releasing hormone (TRH) –> Thyroid-stimulating hormone (TSH)
Corticotropin-releasing hormone (CRF) —> Adrenocorticotropic Hormone (ACTH)
Dopamine Prolactin-inhibiting factor (PIF) –> Prolactin*
(decrease in dopamine will promote prolactin)
Anterior Pituitary:
FLAT (tropic) PEG (direct)
FLAT: FH LH Adrenocorticotropic (ATCH) Thyroid-stimulating hormone (TSH) PEG: Prolactin Endorphin Growth hormone
Antidiuretic Horomone (ADH) or Vasopressin
secreted in response to low blood volume or high blood osmomolarity. Increasing reabsorption of water in the collecting duct of the nephron. increasing blood volume and decreasing blood osmolarity
- Increases blood volume and decreases blood osmolarity.
Oxytocin
Secreted during childbirth and promotes uterine contractions and milk secretion during lactation.
Thyroid
TRH –> TSH
The thyroid is controlled by the thyroid-stimulating hormone.
TSH will stimulate the thyroid gland and follicular cells will produce T3 ( Triiodothyronine) and T4 (Thyroxine)
Hypothyroidism
deficiency in iodine or inflammation of the thyroid
decrease in body temp, slow respiratory, slow heart rate, weight gain
Hyperthyroidism
excess of thyroid hormones may result in tumor
high body temp, high respiratory and heart rate, weight loss
Calcitonin
produced by parafollicular cells. Decreases plasma calcium concentration by promoting calcium in the kidney, decreasing calcium absorption in the gut, and promoting calcium storage in bone.
DECREASES BLOOD CALCIUM CONCENTRATION
Parathyroid hormone (PTH)
The parathyroid gland releases PTH
PTH INCREASES BLOOD CALCIUM CONCENTRATION
PTH raises blood calcium level, by decreasing excretion of calcium by the kidney, increasing absorption of calcium in the gut via vitamin D, and increasing bone resorption, thereby freeing calcium.
PTH and Calcitonin
PTH increases calcium levels
Calcitonin decreases calcium level
Adrenal Cortex secretes Corticosteroids
Corticosteroids: Glucocorticoids: sugar Mineralocorticoids: salt Cortical sex hormones: sex MNEMONIC: The function of corticosteroids: The 3 S's -Sugar -Salt -Sex
Glucocorticoids
cortisol or cortisone increases glucose concentration, reduces protein synthesis, inhibits inflammation.
[CRF –> ATCH –> release of gulcocorticoids]
Mineralocorticoids
Such Aldosterone promotes sodium reabsorption. Aldosterone also increases K+ and H+ ions excretion.
-Aldosterone is regulated by the renin-angiotensin-aldosterone system, not by ACTH.
Aldosterone –> increases blood volume with no effect on blood osmolarity.
Cortical Sex Hormone
include androgen and estrogen in both male and female
Adrenal Medulla
responsible for the secretion of catecholamines hormones
Catecholamines: Epinephrine and Norepinephrine
involved in “fight or flight situation”
Cortisol involved in long-term stress response
Catecholamines involved in short-term stress respone