Endocrine

Question 1

What are the causes of metabolic alkalosis with low/normal bp?

Answer 1

Bartter Syndrome
Gitelman syndrome
Cystic fibrosis

Question 2

What conditions cause Metabolic alkalosis and high bp?

Answer 2

Primary hyperaldosteroneism
Pseudo hyperaldosteroneism
Renal artery stenosis
Renin-producing tumour
Adrenal carcinoma
Liquorice ingestion

Question 3

What are the three conditions that most commonly cause precocious puberty?

Answer 3

Hydrocephalus
Neurofibromatosis type 1 (NF1)
Tuberous Sclerosis

Question 4

What is first line management in PCOS?

Answer 4

Weight loss

Question 5

High insulin and low blood glucose is always pathological. What are differentials ?

Answer 5

Insulinoma
Diabetic overdose or factitious disorder imposed on another (FIDA) - c-peptide levels will be low.

Question 6

Define precocious puberty

Answer 6

Before 8 - girls
Before 9- boys

Question 7

Neonatal hypoglycaemia, macroglossia,
Gigantism

Answer 7

Beckwith Wiedemann Syndrome