Endocrine

Question 1

Type 2 DM medication weights

Answer 1

Weight LOSS = GLP-1, SGLT-2 inhibitors

Neutral: Metformin, Gliptins

Weight GAIN: Insulin, Pioglitazone, Sulphonylureas

Question 2

Corticosteroids SE’s

Answer 2

Cushing’s syndrome
Osteoporosis
Retardation of growth
Thin skin
Immunosuppression + insomnia
Chorioretinopathy
Oedema (water retention)
STriae
Emotional disturbance
Rise in BP (hypertension)
Obesity (truncal)
Increased hair growth (hirsutism)
DM (hyperglycaemia)
.
Ulcers (peptic)
Suppression (adrenal)
Electrolyte imbalance = hypokalaemia

Question 3

Drugs to stop temporarily in when DM pt is ill (SADMAN)

Answer 3

SGLT-2i = dehydration can lead to AKI
ACEi = dehydration can lead to AKI
Diuretics = dehydration can lead to AKI
Metformin = dehydration and risk of lactic acidosis
ARBs = dehydration can lead to AKI
NSAIDs = dehydration can lead to AKI