Antidotes Flashcards

1
Q

Apixaban

A

Andexxanet alfa

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2
Q

Dabigatran

A

Idarucizumab

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3
Q

Rivaroxaban

A

Adexanet alfa

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4
Q

Heparin

A

Protamine sulphate

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5
Q

Alcohol withdrawal

A

Chlordiazepoxide

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6
Q

Paracetamol

A

Acetylcysteine

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7
Q

Methotrexate

A

Folinic acid = calcium folinate

Folinic acid is used with cytotoxic drugs

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8
Q

Warfarin

A

Vitamin K

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9
Q

Opioid or narcotic analgesics

A

Naloxone

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10
Q

Insulin

A

Glucose

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11
Q

Digoxin

A

Digoxin-specific antibody

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12
Q

Iron

A

Desferrioxamine mesilate

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13
Q

Benzodiazepines

A

Flumazenil injection

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14
Q

TCAs

A

Activated charcoal

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15
Q

Loperamide

A

Naloxone

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16
Q

Phenothiazines (Prochlorperazine)

A

Procyclidine

17
Q

Carbamazepine

A

Activated charcoal

18
Q

Dapsone

A

Activated charcoal

19
Q

Phenobarbital

A

Activated charcoal

20
Q

Quinine

A

Activated charcoal

21
Q

Theophylline

A

Activated charcoal

22
Q

Hypoglycaemia

A

If pt is conscious and able to swallow:
PO fast-acting carbohydrate:
- 4 - 5 glucose tabs
- 3 - 4 heaped teaspoonfuls of sugar
- 150 - 200mL fruit juice
Repeat every 15mins for 3 cycles.

If pt is unconscious and can’t swallow:
IM Glucagon - if unresponsive after 10mins: IV glucose

23
Q

Torsade de Pointes (QT Prolongation)

A

IV MgSO4

BB (not sotalol) may be considered

24
Q

Paroxysmal Supraventricular Tachycardia

A

Terminates spontaneously on its own

Reflex vagal nerve stimulation

IV adenosine (CI in COPD/asthma)

IV Verapamil

25
Q

CCB

A

Activated charcoal

If severe: CaCL or calcium gluconate

26
Q

Copper

A

Penicillamine

27
Q

BB

A

Glucagon