Endochondral Ossification

Question 1

What type of tissue does endochondral ossification originate from?

Answer 1

fetal skeleton made out of hyaline cartilage that end up forming chondroblasts

• surrounded by the perichondrium

Question 2

what do chondroblast make?

Answer 2

ground substance

Question 3

chondroblast entrapped in lacunae become…

Answer 3

chondrocytes

Question 4

the process of chondrocytes growing in size is called

Answer 4

hypertrophy

• due to the chondrocytes being entrapped in the lacunae they begin to grow in size

Question 5

what cause chondrocytes to die?

Answer 5

after chondrocytes hypertrophy; causing the lacunae to grow bigger and bigger to which then the ground substance begins to calcify; w/ no nutrients passing through they die.

Question 6

What does the remaining hyaline cartilage become?
where are they found?

Answer 6

nothing but bone

the remaining hyaline cartilage remains at the epiphyseal plates and articular plates for growth until we become adults turning the epi plates to epi lines

Question 7

What do epiphyseal plates become? When does this occur?

Question 8

What occurs to the cartilage and bone production as we age?

Question 9

Primary ossification forms as ___________ and ____________ then go into spaces left by chondrocytes and produce _______ replacing _____________

Answer 9

capillaries
osteoblasts
osteoid
cartilages

Question 10

Secondary ossification centers forms at the ________ similar to _____________________ center forming _______bone

Answer 10

epiphysis
primary ossification
spongy