Endocarditis, Myocarditis, Pericardial Disorders, and Cardiac Neoplasia Flashcards

1
Q

True or False: DMVD has been shown to be a risk factor for infectious endocarditis

A

FALSE

subaortic stenosis is a risk factor for endocarditis

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2
Q

What is the most common presenting complaint for a patient with infectious endocarditis?

A

LAMENESS

(+ fever)

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3
Q

What are the non-cardiac complications that occur with infectious endocarditis?

A
  1. Polyarthritis
  2. Glomerulonephritis
  3. Thromboembolic disease (due to loss of AT3)
  4. CHF + arrhythmias
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4
Q

What type of murmur would you expect to hear in a patient with endocarditis and vegetative lesions on the mitral valve?

A

Left apical systolic murmur (due to mitral regurg)

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5
Q

What type of murmur would you expect to hear in a patient with infectious endocarditis and vegetative lesions on the aortic valve?

A

Left basilar diastolic murmur (due to aorta regurg) + bounding femoral pulses

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6
Q

Infectious endocarditis that has progressed to CHF is usually _____ sided

A

left

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7
Q

List the most common causative agents associated with infectious endocarditis

A
  1. Staph intermedius
  2. Staph aureus
  3. Strep canis
  4. E. coli
  5. Pseudomonas
  6. Bartonella
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8
Q

What is the antibiotic therapy protocol for endocarditis?

A

Long-term bactericidal Abx

  • Beta lactam + Enrofloxacin
  • Given IV for 1-2 weeks, then PO for 6-8 weeks

(+ CHF meds if present)

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9
Q

True or False: Fluid therapy, such as SQ fluids, should be given to a patient in CHF

A

FALSE FALSE FALSE contraindicated

(already have volume overload/too much preload to the heart, this would make it worse)

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10
Q

What is the prognosis of a pet with infectious endocarditis?

A
  • Permanent valve damage (regurg) despite resolution
  • Grave prognosis with aortic IE (days)
  • Better outcome if mitral valve IE (> 1 yr)
  • Worse prognosis if: refractory CHF, thromboembolism, or renal failure
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11
Q

An owner brings in a golden retriever with infectious endocarditis and is told by the vet that the prognosis is guarded, the pet may live just days longer. Which valve is likely affected?

A

Aortic valve - grave prognosis

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12
Q

Myocarditis can result in ________ dysfunction and heart failure

A

systolic

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13
Q

________ is a cardiac biomarker that is used in the diagnosis of myocarditis

A

Cardiac troponin I

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14
Q

If you’re a practicing veterinarian in the southern US, ____________ should always be on your list of differentials when suspect of myocarditis

A

Chagas disease - Trypanosoma cruzi

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15
Q

What is the most common cause of acquired pericardial effusion in dogs?

A. Neoplasia
B. Idiopathic
C. Infectious
D. CHF

A

A. Neoplasia

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16
Q

What is the most common cause of acquired pericardial effusion in cats?

A. Neoplasia
B. Idiopathic
C. Infectious
D. CHF

A

D. CHF

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17
Q

How can pericardial effusion lead to cardiac tamponade?

A

When IPP exceeds ICP

Heart can’t expand, diastolic filling decreases (preload decreases), then SV decreases and then CO

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18
Q

Age, breed, and sex predilection associated with pericardial effusion in dogs?

A
  • Middle to older
  • Medium to large breeds (GSD, Goldens, Labs, brachycephalic breeds)
  • Males > females
19
Q

How do dogs with acute pericardial effusion present?

A

On an ER bases for collapse or weakness, +/- acute vomiting

20
Q

How do dogs with chronic pericardial effusion typically present?

A
  • Vague CS
  • Lethargic, exercise intolerance, ABD distension
  • Coughing, panting, tachypnea/dyspnea
21
Q

Pulsus paradoxus is when the arterial pulse pressure decreases during inspiration. This occurs with what heart condition?

A

Pericardial effusion

22
Q

What would you expect to hear during your cardiac and respiratory portion of a PE on a dog with pericardial effusion?

A
  • Muffled heart sounds if large amount of pericardial effusion
  • Lung sounds decreased if pleural effusion
  • Jug distension
  • Tachypnea/Dyspnea
  • If cardiac tamponade: low BP
23
Q

Explain the fluid you would expect to see after performing a pericardiocentesis on a dog with pericardial effusion?

A

Sanguineous (hemorrhagic)

24
Q

CHF due to pericardial effusion is usually _______ sided

25
What valves are most commonly affected by infectious endocarditis?
Mitral and aortic valves (L side of heart)
26
What are the risk factors for developing infectious endocarditis?
1. Bacteremia due to any cause (UTI, pneumonia, pyoderma, infected wound, etc) 2. Subaortic stenosis 3. Immunosupression 4. Dental procedure
27
DDx for a dog presenting with a heart murmur and fever? (cardiac causes)
Infectious endocarditis or myocarditis (NO OTHER HEART DZ CAUSES FEVER)
28
How can infectious endocarditis lead to thromboembolic disease?
Glomerulonephritis causes AT3 to be lost with Albumin Loss of AT3 causes hypercoaguable state and thrombus formation
29
_________ may develop after a respiratory or GI infection, vaccination, surgery, trauma, or drug exposure A. Endocarditis B. Myocarditis C. Pericardial effusion
B. Myocarditis
30
How does Chagas disease typically present in a dog?
- Fever - Enlarged LN - Arrhythmias - Myocardial dysfunction - CHF
31
Most common locations for hermangiosarcoma?
- Right atrium / Right auricle - Spleen - Lungs
32
What is the treatment protocol for a patient with a heart base tumor?
(Chemodectoma) - Pericardiectomy
33
List all the heart conditions resulting in sudden death in dogs and cats
Cats > dogs 1. AVSD 2. HCM 3. RCM Dogs > cats 4. DCM 5. ARVC 6. Subaortic stenosis
34
Which of the following could result in a globoid cardiac silhouette on thoracic radiographs? A. Myocarditis B. Endocarditis C. Pericardial effusion
C. Pericardial effusion
35
Which drug is contraindicated in a patient with cardiac tamponade?
Diuretics (Furosemide) - Already low preload, CO and SV - Dont won't to loose more fluid vol.. will make it worse
36
What is the prognosis for a patient with hermangiosarcoma on the right auricle resulting in pericardial effusion and cardiac tamponade?
Pericardiocentesis + If just on auricle - can be surgically resected Chemo + surgery gives then ~6 months
37
What is the prognosis for a patient with hermangiosarcoma of the right atrium resulting in pericardial effusion and cardiac tamponade?
- Pericardiocentesis - Can't be surgically resected - Tx with doxorubicin gives them ~ 3-4 months Owner usually elects for euthanasia due to poor prognosis
38
Most common breed associated with chemodectomas?
Brachycephalics
39
What disease resolves in 50% of dogs after initial pericardiocentesis?
Idiopathic pericarditis
40
What is a congenital pericardial disease that can be seen in cats?
Perineopericardial Diaphragmatic hernia (PPDH)
41
What is the treatment protocol for a patient with perineopericardial Diaphragmatic hernia (PPDH)
If asymp - no tx needed If symp - surgical correction
42
What is PPDH?
Abnormal opening between the pericardial sac and peritoneal cavity resulting in herniation of the liver, gall bladder, diaphragm, etc
43