Endo Path - Misc. (FA) Flashcards

1
Q

What is the cause of carcinoid syndrome?

A

Carcinoid tumor secretes 5-HT

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2
Q

What is the most common cancer that causes carcinoid syndrome?

A

Metastatic Sm. Bowel tumors

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3
Q

What are the common symptoms of a carcinoid tumor?

A

Recurrent diarrhea, flushing, asthmatic wheezing, right sided valvular disease

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4
Q

Increased 5-hyproxyindoleacetic acid (5-HIAA) in urine and niacin deficiency?

A

Carcinoid tumor

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5
Q

What is the cause of Zollinger-Ellison syndrome?

A

Gastrin secreting tumor of pancreas or duodenum

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6
Q

Second most common cause of PUD?

A

ZE syndrome

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7
Q

What are the three Ps of MEN1?

A

Pituitary
Parathyroid
Pancreas
Think of the diamond

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8
Q

What are the conditions of MEN2A?

A

Medullary thyroid
Parathyroid
Pheo
Think of the square

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9
Q

What are the conditions of MEN2B?

A

Medullary thyroid
Mucosal
Pheo
Think of the triangle

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10
Q

Which form of MEN is associated with marfanoid habitus?

A

MEN 2B

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11
Q

What are the most common hormones secreted in MEN 1?

A

Prolactin, GH, Insulin, Gastrin, VIP (GI issues)

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12
Q

What is secreted by a medullary thyroid carcinoma and its effects?

A

Calcitonin: reduces bone reabsorption –> low Ca++

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13
Q

What is the inheritance pattern of MEN?

A

AD

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14
Q

What gene is associated with MEN 2A and 2B?

A

RET

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