Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Endo / Repro > Endo Path - Diabetes (FA) > Flashcards

Endo Path - Diabetes (FA) Flashcards

1
Q

What vascular pathology is related to Diabetes?

A

Small vessel: hyaline arteriolosclerosis

Large vessel: Artherosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common cause of death in diabetes?

A

MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the pathophysiology of neuropathy and cataracts in diabetes?

A

Sorbitol accumulation due to aldose reductase and decreased or absent sorbitol dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are lab tests used to confirm diabetes?

A

Fasting glucose (>120), glucose tolerance test (> 140 at 2 hrs, > 126 overnight), and HbA1c (>8 is a predictor of last 3 months)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the pathology of DM 1?

A

Autoimmune against B-cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the pathology of DM2?

A

Insulin resistance, progressive pancreatic failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Does DM1 or DM2 have a higher genetic component?

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the HLA associations with DM1?

A

HLA-DR3 and 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Is ketoacidosis more common in DM1 or DM2?

A

DM1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Leukocytes in Islets?

A

DM1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Amyloid deposits in Islets?

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the pathophysiology of diabetic ketoacidosis?

A

Increased stress (infection) –> increased fat breakdown –> increased ketogenesis –> Increased ff. –> ketone bodies produced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In what form are the majority of ketoacids produced in DKA?

A

B-hydroxybutyrate > acetoacetate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

15 year old presents with Kussmaul respirations, nausea,/vomting, abdominal pain, psychosis, and fruity breath smell?

A

DM1, DKA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the treatment for DKA?

A

IV fluids, IV insulin, K+, and glucose (if necessary)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How would you test for indogenous insulin production?

A

C-peptide levels - these are only produced during indigenous vs. insulin administration

17
Q

What is an insulinoma and the pathology?

A

B-cell tumor –> produce a lot of insulin –> hypoglycemia

Episodic CNS symptoms

Endo / Repro (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions