Endo Misc Flashcards

1
Q

What is the primary screening test for Acromegaly/Gigantism?

A

Insulin Growth Like Factor will be increased

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2
Q

What test confirms Acromegaly/Gigantism?

A

Oral glucose suppression test: Increased GH levels

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3
Q

What medication causes gynecomastia?

A

Spironolactone

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4
Q

DKA is MC seen in

A

T1DM

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5
Q

HHS is MC seen in

A

T2DM

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6
Q

What major metabolic imbalances are present in DKA?

A

acidemia

hyperketonemia

Hyperglycemia

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7
Q

CPx of DKA

A

abdominal pain, vomiting, and fatigue

Fruity Breath

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8
Q

Dx for DKA

A

Glucose >250

Ketonuria

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9
Q

Dx for HHS

A

Glucose > 600

Increased Serum Osmolarity

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10
Q

Critical 1st step of managing DKA/HHS

A

Isotonic 0.9% NS

once hypotension resolves, then:

0.45% NS

When glucose levels = 250, switch to D5 0.45 (1/2) NS

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11
Q

Next steps of Mgmt for DKA/HHS

A

regular insulin & potassium

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12
Q

abnormal findings on thyroid function tests that occur in the setting of a nonthyroidal illness

A

Euthyroid Sick Syndrome

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13
Q

Dx for Euthyroid Sick Syndrome

A

Decreased T4/T3 + Decreased TSH

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14
Q

Triad of Grave’s Disease

A
  1. diffuse goiter
  2. exophthalmos
  3. pretibial myxedema
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15
Q

TSB receptor antibodies

A

Graves Disease

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16
Q

RAIU scan will show _______ uptake in Grave’s Disease

A

RAIU scan will show increased diffuse uptake in Grave’s Disease

17
Q

MC therapy used for Grave’s Disease

A

Radioactive Iodine: destroys thyroid gland

18
Q

Tx for Grave’s Disease

A

Methimazole or PTU

BB for symptomatic relief

19
Q

Plummers Disease

A

toxic multinodular goiter

20
Q

CPx for toxic multinodular goiter/Toxic Adenoma

A

Both TMG & TA:

  • diffuse enlarged thyroid
  • NO skin/eye changes

Compressive sxs: dyspnea, dysphagia, stridor, hoarseness

21
Q

RAIU scan shows ___________ for TMG

A

RAIU scan shows patchy areas of both increased and decreased uptake for TMG

22
Q

RAIU scan shows ___________ for TA

A

RAIU scan shows Increased local uptake (hot nodule) for TMG

23
Q

Tx for TMG & TA

A

same as Graves

24
Q

What DM meds cause hypoglycemia?

A

Sulfonylureas: Glyburide, Glipizide

Meglitinides: “glinides”

All Insulin

25
Q

fatal complication of untreated thyrotoxicosis after a precipitating event

A

Thyroid Storm

26
Q

CPx of Thyroid Storm

A

hypermetabolic state: palpitations, tachy, a-fib, high fever, N/V, psychosis, tremors

27
Q

Labs in Thyroid Storm

A

Same as Graves

28
Q

Tx for thyroid storm

A

Traditionally:

BB

Dexamethasone (impairs hormone production)

PTU

Potassium Iodide

**Do not give PTU or iodide if exogenous overdose of levothyroxine**

29
Q
A