ENDO Flashcards
Whipple’s Triad:
_Blood glucose < 70mg/dl
_Signs and symptoms (confusion, irritability, fatigue, anxiety, sweating, irregular heart rhythm)
_Signs and symptoms resolve with glucose elevation
CLINICAL MANIFESTATIONS:
_Neuroglycopenic (Alterations in consciousness, Lethargy, Confusion, Combativeness, Agitation, Unresponsiveness)
_Sympathomimetic (anxitety, nervousness, irritability, nausea, vomiting, palpations, tremors)
Hypoglycemia
_Generally asymptomatic
_Early sensory nerve toxicity (subtle lower extremity paresthesia)
RISK FACTORS:
_Family History
_Obesity
_Diet
_Physical inactivity
_Race
_Delivered a baby weighing 9 lbs
Pre-Diabetes
_Polyuria (excessive urination)
_Polydipsia (excessive thirst)
_Polyphagia (excessive hunger)
Unexplained weight loss
_Poor wound healing
_Blurred ision
_Prone to infection (candidal vaginitis and balanitis)
_Recurrent UTI
Diabetes Type I
_Polyuria _Polydipsia
_Candida vaginitis may be initial symptom in women
ASSOCIATED SYMPTOMS:
_Hypertension
_Dyslipidemia
_Atherosclerosis
Diabetes Type II
_Asymptomatic
_Abnormal enlargement of the thyroid gland
_Iodine deficiency
_Hoarsness / vocal cord paralysis _Nodules in men / young women _Solitary, firm, large, and fixed _Enlarged cervical lymph nodes _Metastatic leisions
HIGH RISK OF MALIGNANCY:
_History of head/neck radiation _Family history of thyroid cancer _Personal history of malignancy
Thyroid Nodule
_Weight gain
_Fatigue
_Cold intolerance
_Constipation
_Depression
_Menorrhagia
_Hoarseness
_Dry skin
_Bradycardia
_Delayed deep tendon reflex (+1)
Hypothyroidism
_Sweating
_Weight loss
_Heat intolerance
_Diarrhea
_Anxiety
_Menstrual irregularity
_Tachycardia
_Palpitations
_Tremor
_Hyperreflexia (+4)
_Exophthalamos
_Lid lag
Hyperthyroidism
weakness
abdominal pain
nausea / vomiting / diarrhea
fever
confusion
confusion
hypertension
dehydration
Skin hyperpigmentation
Adrenal Crisis
Chronic
Fatigue
Weakness
Abdominal pain
Nausea / Vomiting / Diarrhea _Muscle and joint pain Weight loss /
Anorexia
Hypotension
Amenorrhea
Skin
hyperpigmentation
Adrenal Insufficiency
Adrenal Insufficiency
RED FLAGS:
_Asymetry
_Density located away from subareolar _Nipple retraction
_Nipple bleeding / discharge
_Unusual firmness
Gynecomastia
3 OR MORE OF THE FOLLOWING:
Abdominal obesity
Triglycerides > 150mg/dL
HDL < 40mg/dL (men)
HDL < 50mg/dL (women)
Fasting glucose > 110mg/dL
Hypertension
Metabolic Syndrome
