Endo

Question 1

Congenital causes of PRIMARY hypothyroidism

What will Free & total T4 be compared to TSH levels

Answer 1

Thyroid dysgenesis (ectopy, hypoplasia) 
TSH resistance (mutation in the TSH receptor gene leads to thyroid insensitivity to TSH on thyroid gland and reduced synthesis of T4)

Dec free/total T4
INC TSH