Drugs

Question 1

Main difference between first-generation and second-generation anti-histamines

Answer 1

First-gen have more side-effects such as anticholinergic, anti- alpha adrenergic (postural dizziness, falls) and anti-serotonergic (appetite stimulation, weight gain)

First gen: chlorpheniramine, diphenhydramine, hydroxyzine, promethazine.

Second-gen do not have the same degree of antimuscarinic, antiserotonergic, and antiadrenergic properties and their side effects are minimal.

Second gen: loratadine, cetrizine

Question 2

What is another name for atovaquone-proguanil treatment?

Answer 2

Artemisinin

this is for chloroquine resistant malaria- which most malaria will be resistant so just use atovaquone