endo 1 W7 Flashcards
where is the pituitary gland located?
depression in sphenoid bone - hypophyseal or pituitary fossa
what is the pituitary fossa covered in? what passes through this?
shelf of dura - sellar diaphragm
infundibulum (pituitary stalk) passes through this
where are the cell bodies, axons and synapses of the magnocellular neurons located?
cell bodies - supraoptic and paraventricular nuclei of hypothalamus
axons - travel in pituitary stalk
synapses - posterior pituitary
what hormones travel down the axons of the magnocellular neurons?
oxytocin (cells from PVN) and vasopressin (cells from SON)
what hormones are made in the anterior pituitary? how is their release controlled?
ACTH
LH
FSH
TSH
GH
prolactin
release controlled by inhibitory and releasing hormones from the hypothalamus (travel via pituitary portal system)
relation of hypothalamus etc with other structures?
above optic chiasm
infundibulum emerges between optic chiasm and mammillary bodies
what structure is found immediately below the pituitary fossa?
sphenoid sinus
thyroid gland features?
left lobe
isthmus
right lobe
what nerve do the superior and recurrent laryngeal nerves both originate from?
vagus nerve (CN-X)
what nerve is vulnerable to damage during thyroid surgery?
what effect would this damage have?
the recurrent laryngeal nerve
hoarseness, potential difficulty breathing
what hormones are released by the thyroid gland? how is their release controlled?
T3, T4, Calcitonin
controlled by TSH release from anterior pituitary
where are the parathyroid glands found and what hormone do they release?
posterior aspect of the thyroid gland
release parathyroid hormone
blood supply to the thyroid?
superior thyroid artery (branches off external carotid)
inferior thyroid artery (branches off thyrocervical trunk, which is a branch of the subclavian)
which veins do the thyroid veins drain into?
superior and middle thyroid veins -> internal jugular vein
inferior thyroid veins -> brachiocephalic veins
what is the blood supply to the parathyroid glands? why is it important to be aware of this during surgery?
primarily branches from inferior thyroid arteries, collateral supply from superior thyroid arteries.
surgery risk of disrupting parathyroid blood supply when thyroid is being removed