Embryonic Cardiac Development Flashcards
What are the stages of embryonic cardiac developement?
Stage 1: single cardiac tube
Stage 2: further differentiation
Stage 3: absorption and septation
What happens in stage 1?
2 cardiac tubes combine to form 1, tube is lined with cardiac jelly and surrounded by myoepicardium mantle
When does stage 1 occur?
around day 22 of gestation
What are the different sections of the single tube?
-truncus arteriosus
-bulbis cordis (2 sections, conus cordis and truncus conus)
-primitive ventricle
-primitive atrium
-sinus venous
What does the truncus arteriosus become?
aorta and pulmonary artery
What are the sections of the bulbus cordis?
conus cordis and truncus conus
What does the conus cordis become?
LVOT and RVOT
What does the truncus conus become?
RV
What does the primitive ventricle become?
LV
What does the primitive atrium become?
RA and LA
What does the sinus venosus become?
inflow channels, IVC, SVC
What does the extra fold in the sinus venosus become?
eustachian valve
What is the order of blood flow in the primitive heart?
Enters through sinus venosus -> atrium -> primitive ventricle -> bulbus cordus -> truncus arteriosus
What happens in stage 2?
-the tube starts to loop, this is known as atrioventriculobulbo loop
-the top part bends anteriorly and to the right (dextro or d-looping)
When does stage 2 occur?
Tube starts to loops at day 23
Looping is complete at day 24
Stage 2 complete at day 28
What is the atrioventriculobulbo loop?
when the cardiac tube begins to loop at day 23
What us dextro or d-looping?
when the top part of the cardiac tube bends anteriorly and to the right