Embryology Flashcards
How many chromosomes do primary spermatocytes contain?
46
How many chromosomes do secondary spermatocytes contain?
23
What are the 4 daughter cells produced from meiosis II called in spermatogenesis?
Spermatids
What is a spermatid?
An immature male sex cell formed from a spermatocyte, which may develop into a spermatozoon without further division.
What is an oogonium?
An immature female reproductive cell that gives rise to primary oocytes by mitosis.
During fetal development, when is oogenesis paused?
Prophase I of meiosis I
True or False:
Meiosis II is not completed until fertilisation.
True
Where does fertilisation usually occur?
Ampullary region of the fallopian tube
How long are sperm viable for?
Five days
How long is the secondary oocyte viable for?
12-24 hours
What does sperm require to be capable of fertilisation?
Capacitation, meaning the tail of the sperm moves faster, causing the plasma membrane to alter
What is embryonic age?
Time since fertilisation
What is gestational age?
Time since last menstruation
Embryonic age - 2 weeks
What is the germinal stage?
Time from fertilisation to the end of the second week
What is the embryonic period?
Time from the 3rd week to the end of the 8th week
What is the foetal period?
Time from the 9th week to birth at 38 weeks
At what day does implantation usually occur?
Day 6
What does the blastocyst have to lose before it can implant?
Zona pellucida
What is the process of losing the zona pellucida called?
Hatching
What is the zona pellucida thought to prevent?
The morula/blastocyst adhering to the oviduct
What is a morula?
A solid ball of cells resulting from division of a fertilized ovum, and from which a blastula is formed
What does the trophoblast become?
The yolk sac and placenta
What is the trophoblast?
A layer of tissue on the outside of a blastula, supplying the embryo with nourishment and later forming the major part of the placenta.
What is the normal implantation site?
Superior and posterior wall of the uterine cavity
Why is the 2nd week of development known as the weeks of 2s?
- The trophoblast differentiates into 2 layers (cytotrophoblast and syncytiotrophoblast)
- The embryoblast forms 2 layers (the epiblast and hypoblast - the bilaminar embryonic disc)
- The hypoblast contributes to the formation of 2 cavities (the yolk sac and chorionic cavity)
What is the period from weeks 3 to 8 called?
Embryonic period
What are some examples of things that can lead to major congenital malformation during the embryonic period?
Thalidomide, isotretinoin, warfarin, rubella
What are the key events and processes in early development?
Fertilisation, implantation, gastrulation, neurulation, segmentation, folding
What is the epiblast at the end of the second week?
A uniform disk
What marks the start of gastrulation?
Primitive streak