Embryology 3 Flashcards

1
Q

Where does the tubular outgrowth occur? And what does this outgrowth develop into?

A

From the foregut

Develops into trachea and lung buds

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2
Q

When does trachealoesophgus fistula occur?

A

When trachea and esophagus doesn’t separate

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3
Q

WHat does the gut tube form from?

A

Endoderm

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4
Q

At which week does the development of trachea and lung occur? Where?

A

Week 4 of gestation

From ventral wall of foregut

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5
Q

Which derm is involved in the formation of the pleura?

A

Lateral plate Mesoderm

Splacnic = visceral 
Somites = parietal
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6
Q

What does the Oesophagotracheal septum do?

A

then develops between oesophagus and trachea, completely separating them into trachea ventrally and oesophagus dorsally

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7
Q

Define atresia

A

a condition in which an orifice or passage in

the body is (usually abnormally) closed or absent.

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8
Q

Define fistula

A

an abnormal or surgically made passage between a tubular organ and the body surface, or between two hollow or tubular organs, ie. between 2 epithelialized surfaces.

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9
Q

What pleural cavity will somatic mesdoderm layer form?

A

Parietal pleura

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10
Q

What pleural cavity will splachnic mesdoderm layer form?

A

Visceral

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11
Q

What is the gap between parietal and visceral pleurae called?

A

pleuroperitoneal canals

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12
Q

What are the stages from foetal period to postnatal period?

A

Embryonic, pseudo glandular then canalicular then saccular and alveolar

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13
Q

What age does the number of alveolar reach adult number?

A

8 years

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14
Q

What is a surfactant and by which cell is it secreted by?

A

is mixture of phospholipids and proteins secreted by type 2 pneumocytes

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15
Q

What percentage of neonates are effected by Respiratory distress syndrome? And what is the major cause?

A

2%

Surfactant deficiency

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16
Q

Where does the central tendon develop from?

A

Septum transversum

17
Q

Where does the primitive diaphragm develop from?

A

Pleuroperitoneal membranes

18
Q

Where does the median portion and crura of diaphragm form from?

A

Dorsal mesentery of oesophagus

19
Q

Where does the peripheral parts od diaphragm form from?

A

Muscular ingrowth from lateral body walls

20
Q

Which vertebrae is septum transversum initially located?

A

opposite C3-C5 somites (week 3)
Brings down with it spinal nerves C3 – C5
Phrenic nerve

21
Q

What are the three major defects in diaphragm?

A

Failure of the diaphragm to completely close during development
Herniation of the abdominal contents into the chest
Pulmonary hypoplasia

22
Q

What are the two types of hiatal herniae?

A

Sliding and paraesophageal hiatus hernia