Embryology 2 Flashcards

1
Q

GASTRULATION and NEURULATION

A

Formation of germ layers

Formation of neural tube

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2
Q

Describe the location of the Primitive streak

A

formed in the midline of the epiblast by the dipping in of cells (invagination)

Provides an axis

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3
Q

Describe the 3 germ and type of disc

A

Ectoderm
Mesoderm
Endoderm

Trilaminar disc

*Gastrulation

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4
Q

What remnant is the nucleous pulposis of?

A

Notochord

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5
Q

What are the three parts the mesoderm separates into?

A

Paraxial, intermediate and lateral

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6
Q

What does dermtome,myotome and sclerotome form?

A

Dermtome dermis of skin
Myotome muscles
Sclerotome bones including vertebrae

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7
Q

Describe the 3 parts of the somite

A

Dermatome
Myotome
Sclerotome

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8
Q

Describe the intermediate plate mesoderm

A

Urogenital system (kidneys, reproductive)

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9
Q

Define teratology

A

Study of when things go wrong during development

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10
Q

Congenital rubella

A

caused by contraction of german measles when pregnant

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11
Q

Describe the 3 factors the risk posed by a teratogen depends on

A

Exposure during critical periods of development
Dosage of drug/chemical/factor
Genetic constitution of embryo ie some more susceptible than others at equivalent doses etc

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12
Q

Diagnosis of malformations prenatal

A

Blood - AFP
Ultrasound scan – 12 week anomaly scan
Invasive tests: chorionic villus sampling and amniocentesis

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13
Q

Diagnosis of malformations postnatal

A

Hip stability
Testes (descent)
Fingers and toes
Hearing

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