EMBRYO exam 1 Flashcards

1
Q

Neural crest cells form

A

sensory ganglia

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2
Q

Alar plate develops into?

A

dorsal horn- receives sensory input

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3
Q

Basal plate devlops into

A

ventral horn- motor neurons exits to muscles

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4
Q

dorsal ramus innervates

A

back muscles and skin of the back

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5
Q

ventral ramus innervates

A

limbs and everything else

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6
Q

spina bifida occulta

A

failure of the vertebral (neural) arch to form; covered dorsally by skin sometimes tuft of hair

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7
Q

spina bifida - meningocele

A

failure of the vertebral (neural) arch to form; covered dorsally by skin and meninges protrude outward forming a cyst

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8
Q

spina bifida- meningomyelocele

A

failure of the vertebral (neural) arch to form; covered dorsally by skin , meninges and neural tissue/spinal chord protrude outward dorsally forming a cyst

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9
Q

Spina bifid- myeloschisis

A

neural plate doesn’t fold or complete fusion dorsally/ exposed spinal cord

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10
Q

sclerotome development of spinal column

A

c1 somite form cranial half of c2 vertebrae… it splits to allow innervation in between vertebrae and muscle attachment to two different vertebrae

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11
Q

klippel-feil syndrome

A

process of resegmentation by sclerotome is incomplete resulting in fused vertebrae

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12
Q

rib sclerotome of cervical form what

A

anterior tubercle

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13
Q

rib sclerotome of lumbar region

A

transverse process

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14
Q

rib sclerotome of the sacrum region

A

ala (lateral part)

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15
Q

sternum derived from

A

lateral plate mesenchym (mesoderm not sclerotome)

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16
Q

pectus carinatum

A

pectus protrudes

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17
Q

pectus excavatum

A

pectus depression

18
Q

intramembranous bone fromation

A

mesenchym—–>bone such as flat bones of skull ( part of clavicle

19
Q

Endochondral bone formation

A

mesenchyme —–>cartilage——–>bone/ most bones all long bones/vertabrae

20
Q

somatic layer of lateral plate mesoderm makes….

A
Connective tissues (bone, tendons, 
     ligaments, dermis, blood, blood vessels).
21
Q

surface ectoderm makes…

22
Q

myotome of somites

A

skeletal muscle of trunk and limbs

23
Q

limb mesenchyme form lateral plate

A

limb bones

24
Q

apical ectodermal ridge (AER)

A

enduces surrounding mesenchyme to proliferate and grow a limb bud in the proximal to distal direction releases fgf

25
hox genes
control limb position on trunk
26
hox 9
scapula
27
hox 10
humerus/ stylopod
28
hox 11
ulna/radius/zuegopod
29
hox 12
metacarpals// autopod
30
hox 13
digits/autopod
31
amelia
early loss of fribroblast growth factor FGF signaling leads to no limb development
32
meromelia (phocomelia)
late loss of fribroblast growth factor FGF signaling
33
brachydactyly
short digits
34
syndactyly
fused digits
35
polydactyly
extra digits
36
cleft foot
loss of digits and fusion of others (lobster claws) ectrodactyly-split hand/foot/ bifrication of autopod
37
primaxial domain
back shoulder and intercostal muscles
38
abaxial domain
infrahyroid body wall and limb muscle
39
skelatal muscle formation
mesenchyme ----> myoblasts-----.>myotubules---->secondary myotubules----->muscle fiber with innervation
40
motor innervation pattern
proxal to distal
41
amniotic bands
umbilical cord cuts off limbs