EMBRYO exam 1 Flashcards

1
Q

Neural crest cells form

A

sensory ganglia

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2
Q

Alar plate develops into?

A

dorsal horn- receives sensory input

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3
Q

Basal plate devlops into

A

ventral horn- motor neurons exits to muscles

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4
Q

dorsal ramus innervates

A

back muscles and skin of the back

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5
Q

ventral ramus innervates

A

limbs and everything else

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6
Q

spina bifida occulta

A

failure of the vertebral (neural) arch to form; covered dorsally by skin sometimes tuft of hair

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7
Q

spina bifida - meningocele

A

failure of the vertebral (neural) arch to form; covered dorsally by skin and meninges protrude outward forming a cyst

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8
Q

spina bifida- meningomyelocele

A

failure of the vertebral (neural) arch to form; covered dorsally by skin , meninges and neural tissue/spinal chord protrude outward dorsally forming a cyst

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9
Q

Spina bifid- myeloschisis

A

neural plate doesn’t fold or complete fusion dorsally/ exposed spinal cord

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10
Q

sclerotome development of spinal column

A

c1 somite form cranial half of c2 vertebrae… it splits to allow innervation in between vertebrae and muscle attachment to two different vertebrae

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11
Q

klippel-feil syndrome

A

process of resegmentation by sclerotome is incomplete resulting in fused vertebrae

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12
Q

rib sclerotome of cervical form what

A

anterior tubercle

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13
Q

rib sclerotome of lumbar region

A

transverse process

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14
Q

rib sclerotome of the sacrum region

A

ala (lateral part)

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15
Q

sternum derived from

A

lateral plate mesenchym (mesoderm not sclerotome)

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16
Q

pectus carinatum

A

pectus protrudes

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17
Q

pectus excavatum

A

pectus depression

18
Q

intramembranous bone fromation

A

mesenchym—–>bone such as flat bones of skull ( part of clavicle

19
Q

Endochondral bone formation

A

mesenchyme —–>cartilage——–>bone/ most bones all long bones/vertabrae

20
Q

somatic layer of lateral plate mesoderm makes….

A
Connective tissues (bone, tendons, 
     ligaments, dermis, blood, blood vessels).
21
Q

surface ectoderm makes…

A

epidermis

22
Q

myotome of somites

A

skeletal muscle of trunk and limbs

23
Q

limb mesenchyme form lateral plate

A

limb bones

24
Q

apical ectodermal ridge (AER)

A

enduces surrounding mesenchyme to proliferate and grow a limb bud in the proximal to distal direction releases fgf

25
Q

hox genes

A

control limb position on trunk

26
Q

hox 9

A

scapula

27
Q

hox 10

A

humerus/ stylopod

28
Q

hox 11

A

ulna/radius/zuegopod

29
Q

hox 12

A

metacarpals// autopod

30
Q

hox 13

A

digits/autopod

31
Q

amelia

A

early loss of fribroblast growth factor FGF signaling leads to no limb development

32
Q

meromelia (phocomelia)

A

late loss of fribroblast growth factor FGF signaling

33
Q

brachydactyly

A

short digits

34
Q

syndactyly

A

fused digits

35
Q

polydactyly

A

extra digits

36
Q

cleft foot

A

loss of digits and fusion of others (lobster claws) ectrodactyly-split hand/foot/ bifrication of autopod

37
Q

primaxial domain

A

back shoulder and intercostal muscles

38
Q

abaxial domain

A

infrahyroid body wall and limb muscle

39
Q

skelatal muscle formation

A

mesenchyme —-> myoblasts—–.>myotubules—->secondary myotubules—–>muscle fiber with innervation

40
Q

motor innervation pattern

A

proxal to distal

41
Q

amniotic bands

A

umbilical cord cuts off limbs