Elimination studymate Flashcards
1
Q
Time taken for 50% of administered drug to be eliminated
A
Half Life
2
Q
When rate of elimination is directly proportional to drug concentration it is described as
A
First order
3
Q
This phase of metabolism involves conjugation reactions
A
Phase 2
4
Q
The main site of drug metabolism is
A
The Liver
5
Q
Where in the cell are the enzymes involved in phase 1 metabolism found?
A
Smooth endoplasmic reticulum
6
Q
Term used when rate of elimination is independent of drug concentration
A
Zero order
7
Q
The enzymes responsible for of phase 2 metabolism are found mainly in the cell
A
Cytosol
8
Q
The enzymes involved in Phase 1 metabolism
A
Cytochrome P450
9
Q
Which phase of metabolism entails mainly oxidation reactions?
A
Phase 1
