Drug naming and formulation Flashcards

1
Q

The study of the way in which a drug interacts with a receptor is an example of:

A

Pharmacodynamics

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2
Q

The science concerned with formulation of medicines is:

A

Pharmaceutics

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3
Q

what does ‘pharmacodynamics’ mean?

A

What the drug does to the body

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4
Q

With regard to excipients, magnesium stearate is an example of:

A

A lubricant

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5
Q

What does Pharmacokinetics mean?

A

Pharmakon [drug] + Kinesis [movement]
Deals with what the body does to the drug.
(A,D,M,E).

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6
Q

What does Pharmacodynamics mean?

A

Pharmakon [Drug[ + Dynamis [Power]
Deals with what the drug does to the body.
e.g. the study of the drug effects.

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7
Q

What is ‘drug’ also referred to as?

A

Active Pharmaceutical Ingredient (API)

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8
Q

What are excipients?

A

a substance formulated alongside the active ingredient of a medication, used in all dosage forms, and are essential to product performance.

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9
Q

Define and give Examples of the excipients:

Diluents

A
Add bulk (fillers)
- lactose, microcrystalline cellulose
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10
Q

Define and give Examples of the excipients:

Disintegrants

A

Help tablet break up when wet

- starch, bicarbonate

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11
Q

Define and give Examples of the excipients:

Granulants

A

Hold tablet together (binders)

- starches, sugars, cellulose

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12
Q

Define and give Examples of the excipients:

Lubricants

A

Stops tablets sticking together and to machinery during manufacture
- talc, silica, magnesium sterate.

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13
Q

Why are Colourings (excipient) used?

A

Improves appearance and aids identification

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14
Q

what are these used for

1) Chemical name
2) Code / number
3) Generic name
4) trade name

A

1) used by medicinal chemists
2) assigned by manufacturer
3) non-proprietary / approved name
4) Proprietary name
e.g.
1-(2’-hydroxyethyl)- 2 methyl-5-nitroimidazole
8823 RP
Metronidazole
Flagyl(R)

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15
Q

Give some examples of local anaethetics (CAINE)

A

lignocaine
cocaine
prilocaine

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16
Q

Give some examples of Beta Blockers (OLOL)

A

propranolol
atenolol
pindolol

17
Q

Give some examples of Lipid lowering drugs (STATIN)

A

Simvastatin
pravastatin
lovastatin

18
Q

Give some examples of ACE Inhibitors (PRIL)

A

captopril
enalapril
ramapril

19
Q

Give some examples of Angiotensin 2 antagonists (ARTAN)

A

Losartan

varsartan

20
Q

Give some examples of Propton Pump Inhibitors (PPI) (AZOLE)

A

omeparazole

lanzoprazole