Drug naming and formulation Flashcards
The study of the way in which a drug interacts with a receptor is an example of:
Pharmacodynamics
The science concerned with formulation of medicines is:
Pharmaceutics
what does ‘pharmacodynamics’ mean?
What the drug does to the body
With regard to excipients, magnesium stearate is an example of:
A lubricant
What does Pharmacokinetics mean?
Pharmakon [drug] + Kinesis [movement]
Deals with what the body does to the drug.
(A,D,M,E).
What does Pharmacodynamics mean?
Pharmakon [Drug[ + Dynamis [Power]
Deals with what the drug does to the body.
e.g. the study of the drug effects.
What is ‘drug’ also referred to as?
Active Pharmaceutical Ingredient (API)
What are excipients?
a substance formulated alongside the active ingredient of a medication, used in all dosage forms, and are essential to product performance.
Define and give Examples of the excipients:
Diluents
Add bulk (fillers) - lactose, microcrystalline cellulose
Define and give Examples of the excipients:
Disintegrants
Help tablet break up when wet
- starch, bicarbonate
Define and give Examples of the excipients:
Granulants
Hold tablet together (binders)
- starches, sugars, cellulose
Define and give Examples of the excipients:
Lubricants
Stops tablets sticking together and to machinery during manufacture
- talc, silica, magnesium sterate.
Why are Colourings (excipient) used?
Improves appearance and aids identification
what are these used for
1) Chemical name
2) Code / number
3) Generic name
4) trade name
1) used by medicinal chemists
2) assigned by manufacturer
3) non-proprietary / approved name
4) Proprietary name
e.g.
1-(2’-hydroxyethyl)- 2 methyl-5-nitroimidazole
8823 RP
Metronidazole
Flagyl(R)
Give some examples of local anaethetics (CAINE)
lignocaine
cocaine
prilocaine
Give some examples of Beta Blockers (OLOL)
propranolol
atenolol
pindolol
Give some examples of Lipid lowering drugs (STATIN)
Simvastatin
pravastatin
lovastatin
Give some examples of ACE Inhibitors (PRIL)
captopril
enalapril
ramapril
Give some examples of Angiotensin 2 antagonists (ARTAN)
Losartan
varsartan
Give some examples of Propton Pump Inhibitors (PPI) (AZOLE)
omeparazole
lanzoprazole
