Adverse drug reactions studymate

Question 1

Outdated tetracycline can yield a toxic compound that can cause kidney damage. This is an example of …………………….. toxicity

Answer 1

Pharmaceutical toxicity

Question 2

Chemical that causes cancer

Answer 2

Carcinogen

Question 3

Some individuals given suxamethonium as a muscle relaxant, suffer prolonged aponea (shallow breathing) due to deficiency of psuedocholinesterase which would normally metabolize the drug. This is an example of …………………… variation.

Answer 3

Pharmacogenetic

Question 4

A commonly used drug which can cause allergic reactions is

Answer 4

Penicillin

Question 5

This drug can cause inhibition of metabolic enzymes

Answer 5

Cimetidine

Question 6

In some cases toxic damage can occur if drug clearance is reduced due to disease of the liver. This is an example of ………….. toxicity.

Answer 6

Pharmacokinetic

Question 7

This drug can act as an inducer of metabolic enzymes

Answer 7

Rifampicin

Question 8

Chemical substance that causes foetal malformation

Answer 8

Teratogen

Question 9

This drug can produce pseudo-allergic reactions in asthmatic individuals

Answer 9

Aspirin

Question 10

Digoxin (used for heart failure) may produce toxic effects if there is fall in potassium levels concentration, because these ions normally compete with the drug for binding sites on cardiac muscle. This is an example of ……………. toxicity.

Answer 10

Pharmacodynamic

Question 11

Prolonged use of anti-inflammatory corticosteroids (e.g. to treat arthritis) can lead to

Answer 11

Physical dependence