Electron Transport by the Resp. Chain - ME Flashcards
Where is the respiratory chain located?
Embedded in the inner mitochondrial membrane
What are some advantages due to the location of the respiratory chain?
It is not limited by the rate of diffusion and no mobile carrier needed
What are the 5 classes of oxide/red centers?
FP, FeS, Q, Cyt, Cu
How many electron can a flavin donate and accept?
2 electrons
Where does iron-sulfur center obtain their electrons?
From Flavins and Ubiquinone (Q)
How many electrons can iron-sulfur donate/accept?
1 electron
Acidification of iron-sulfur group causes?
Production of H2S gas
List 8 key properties of Ubiquinone
- donate/accept 2 electrons
- mech. 1,6-addition
- 10 isoprenoid chains in mammals
- very hydrophobic
- Cofactor
- 10-fold excess over the other compounds
- acts as an electron buffer
- Mobile carrier
How many electrons can hemes donate/accept?
1 electron
Heme is covalently attached to 2 cysteine side chains in?
Cyt c and c1
The iron atom of the heme group in cytochrome c coordinate to?
A methionine and a histidine side chain in addition to the 4 porphyrin-ring nitrogens
Where are Copper centers located and how many electrons do they donate/accept?
They are located in cytochrome oxidase (complex 4) and they donate/accept 1 electron
What are the differences between Cu A vs Cu B?
Copper center A contains 2 coppers and copper center B along with the heme iron of Cyt a3 forms the O2 bin gins site at the end of the respiratory chain
