Eicosanoids(PG,TAX,Lekotrienes), Asthma, COPD

Question 1

nsaids

Answer 1

aspirin, ibuprofen, 나프록센, 인도메타신

Question 2

The platelet actions of TXA2, are restrained in vivo by ___________.

Answer 2

PGI2

Question 3

clopidogrel

Answer 3

항혈소판제

Question 4

chronic NSAID consumption can cause __________ characterized by chronic nephritis and renal papillary necrosis.

Answer 4

analgesic nephropathy

Question 5

acute inflammation이 일어났을 때 resolution(복구)하면서 생성하는 lipoxin은?

Answer 5

염증인자인 류코트렌과 비슷하게 생겼지만 정반대의 반응을 함

Question 6

______________: mimic the functions of lipoxins as anti-inflammatory agents.
another endogenous mechanism of anti-inflammation. 아라키돈산이 아스피린에 의해 아세틸화된 형태

Answer 6

epi lipoxins (ATLS)

Question 7

DLCO의 의미는?

Answer 7

폐용적

Question 8

____________: eosinophilic inflammation of the bronchial mucosa.

Answer 8

lymphocytic

Question 9

Two humanized monoclonal antibodies targeting IL-5, __________ and __________, and another targeting the IL-5 receptor, _______________ have recetly been developed for the treatment of eosinophilic asthma.

Answer 9

mepolizumab, reslizumab, benralizumab

Question 10

mepolizumab

Answer 10

anti IL-5, asthma 치료제

Question 11

reslizumab

Answer 11

anti IL-5, asthma 치료제

Question 12

benralizumab

Answer 12

anti IL-5R, asthma 치료제

Question 13

dupilmab

Answer 13

anti IL-4Ralpha, asthma 치료제

Question 14

이물질 흡입 또는 찬 공기 유입시 부교감신경의 활성으로 인한 기관지 수축 반응이 일어남. 이때 어떤 약을 써야함?

Answer 14

ipratropium, tiotropium

Question 15

theophylline

Answer 15

PDE inhibitor, camp 증가시켜 기관지 확장시켜 천식 치료에 사용함

Question 16

____________: release of proteases results in alveolar wall destruction.

Answer 16

emphysema

Question 17

____________: mucus hypersecretion

Answer 17

chronic bronchitis

Question 18

slidenafil

Answer 18

PDE5 inhibitor

Question 19

albuterol(salbutamol)

Answer 19

SABA, 천식약

Question 20

salmeterol

Answer 20

LABA

Question 21

formoterol

Answer 21

LABA

Question 22

methylxanthines

Answer 22

PDE inhibitor

Question 23

indacaterol

Answer 23

ultra-LABA

Question 24

Olodaterol

Answer 24

ultra-LABA

Question 25

vilanterol

Answer 25

ultra- LABA

Question 26

Tulobuterol

Answer 26

경피 흡수형 기관지 확장제

Question 27

roflumilast

Answer 27

PDE4 inhibitor

Question 28

Aclidinium

Answer 28

LAMA

Question 29

Uneckudubuyn

Answer 29

LAMA

Question 30

Hydrocortisone

Answer 30

corticosteroids

Question 31

Beclomethasone

Answer 31

corticosteroids

Question 32

Budesonide

Answer 32

corticosteroids

Question 33

Fluticasone

Answer 33

corticosteroids

Question 34

Flunisolide

Answer 34

corticosteroids

Question 35

Triamcinolone acetonide

Answer 35

corticosteroids

Question 36

cromolyn

Answer 36

mast cell stabilizer

Question 37

ketotifen(Zaditor)

Answer 37

mast cell stabilizer

Question 38

Zileuton

Answer 38

5-lipoxygenase(LOX) inhibitor

Question 39

zafirlukast

Answer 39

LTD4-R blocker

Question 40

montelukast

Answer 40

LTD-4R antagonist

Question 41

omalizumab

Answer 41

anti-IgE