Eczema

Question 1

What is atopic eczema?

Answer 1

Chronic atopic condition caused by defects in the normal continuity of the skin barrier, leading to inflammation in the skin

Question 2

Mutation in what gene is involved in atopic eczema

Answer 2

Filaggrin

Question 3

What is allergic contact eczema?

Answer 3

Delayed type 4 hypersensitivity reaction

Allergen in contact with the skin

Question 4

What is irritant contact eczema?

Answer 4

Non-specific physical irritation rather than a specific response to an allergen

Question 5

Presentation of eczema

Answer 5

Itchy and dry skin
Ill-defined erythema and scaling
Flexural distribution

Question 6

Chronic changes seen in eczema

Answer 6

Lichenification

Excoriation

Question 7

Lesion in eczema herpeticum

Answer 7

Monomorphic punched out lesions

Question 8

Treatments for eczema

Answer 8

Emollients
Avoid irritants
Topical steroids
Topical calicneurin inhibitors (atopic eczema)
Dupilumab (IL-4/IL-13 monoclonal antibody)
Phototherapy (UVB)
Systemic immunosuppressants

Question 9

Presentation of seborrhoeic eczema

Answer 9

Itchy rash with flaky scales

Lesions are found on the scalp, eyebrows, nasolabial fold, upper sternum and back