Ecology of disease emergence - T Flashcards
epidemiological triad
host, environment, agent all connected to each other and to a vector
zoonotics
diseases and infections of vertebrate animals that can be transmitted to humans
zoonotic spillover
reservoir hots come in direct contact with humans and wild animals
eating or close contact transfers even more
loss of forest cover and consumption of bushmeat drives contact between humans and wild hosts, leading to infections
because of forest fragmentation, increased edge of contact between humans and wild reservoirs of new pathogens
mutations in flu virus
a person immunity to one antigen ( H or N) does not protect them against different antigen combinations
many viruses, many different combinations, many mutations
antigenic drift
point mutations cause small changes in surface antigens
can lead to regional epidemics in populations that have had no previous exposure.
antigenic SHIFT
the process by which the whole antigenic (H-N) combination changes
large pieces of genome are exchanges between different viruses attacking the same cell
this can cause pandemics. new to everyone.
pigs are mixing vessels for virus reassortment from birds to humans
pigs,humans,birds,mongoose, bats