EBM Flashcards
What type of question asks for general knowledge about a condition or thing?
Background questions
- a question with a root and a verb
- a disorder, test, treatment, or other aspect of health care
How long is the incubation period for mono?
Example of what type of question?
Background question
What type of question asks for specific knowledge to inform clinical designs or actions?
Foreground questions
PICO
In children, what is the incidence of rheumatic fever in treated vs untreated patients with strep group A?
Example of what type of question?
Foreground questions
What is POEM? DOE?
Patient-oriented evidence that matters
-mortality, morbidity, quality of life
Disease-oriented evidence
-pathophysiology, pharmacology, etiology
If the POEM contradicts the DOE for a drug, what do you do?
Do not use the drug
What is the EER?
Experimental event rate- the risk of adverse effects in treated group
What is the CER?
Control event rate- the risk of adverse effects in the control group (those with placebo or standard therapy)
If the RR is less than 1 the treatment is ____. If the RR is equal to 1 the treatment is ____. Greater than 1 the treatment is _____.
Effective
Neutral
Harmful
The RRR value tends to be independent of the ____.
CER
ARR increases as ___ increases.
CER
The number of patients who must be treated to have 1 less adverse outcome is called what? What is ideal for this?
NNT- number needed to treat
NNT = 1
The ____ is essentially the CER expected in your patient.
PEER
Equation for the EER
The new treatment disease / total getting new treatment
Total is diseased + not diseased
Equation for CER
The diseased getting placebo tx / total getting placebo
Total is diseased and not diseased getting the placebo tx
