Early pregnancy

Question 1

Complete mole- haploid or diploid?

Answer 1

Diploid

Question 2

What is the origin of complete mole 75-80%?

Answer 2

Duplication of single sperm fertilising an empty ovum

Question 3

Dispermatic ferilisation empty ovum in what percentage?

Answer 3

20-25%

Question 4

90% of partial moles are what?

Answer 4

Triploid
2x paternal haploid and 1 x maternal

Usually evidence of fetal RBCS

Question 5

Which ethnicity GTD increased in?

Answer 5

Asians

Question 6

What is the cure rate?

Answer 6

98-100%

Question 7

Chemo rates for partial and complete?

Answer 7

0.5-1% partial

13-16% complete

Question 8

Incidence of GTD

Answer 8

1/700

1600 per year

Question 9

RFs

Answer 9

extremes of age

Prev molar

Question 10

Why should people treated for trophoblastic disease avoid pregnancy for a year?

Answer 10

Risk of relapse- 2% low risk and 3 % high risk.

Highest risk in the first year

Question 11

What is the recurrance rate of molar?

Answer 11

1%

1/55 1 mole

1/10 2 mole

Question 12

What is the scoring system used to score severity?

Answer 12

figo 2000

<6 low risk
>7 high risk

Question 13

Post treatment when can hormonal contraceptives be used?

Answer 13

when hcg normal