Ear and Orphanyx

Question 1

What is the definition for sublingual drug delivery, buccal drug delivery and local drug delivery?

Question 2

What type of epithelium are present in the oral cavity and where are they located?

Question 3

what is the benefit of keratinised layer?

Question 4

What is oral transmucosal drug delivery?

Question 5

What are the advantages and disadvantages of transmucosal drug delivery? 

Question 6

What are the three main parts of the pharynx?

Question 7

What are the physiological barriers affecting oral transmucosal drug delivery? 

Question 8

What is mucoadhesion?

Question 9

Which part of the mouth produces a watery secretion of the mouth? 

Question 10

What is the difference between the paracellular route vs the transcellular route? 

Question 11

What region of the oral mucosa has the greatest epithelial thickness?

Question 12

What are the two types of epithelial? 

Question 13

Which route allows for a larger drug delivery absorption and what characteristic gives it this trait?

Question 14

Which route is likely to allow the drug into the systemic circulation? 

Question 15

What issues do we have with semi-solid dosage forms?

Question 16

What is the mode of action for chewing gums? 

Question 17

What barrier is predominantly present for chewing gum formulation? 

Question 18

What are solid dosage formulations? What is a disadvantage of this formulation?

Question 19

What are the bioadhesive formulations?

Question 20

What are the advantages of the spray? 

Question 21

What can we do to optimize the formulations? 

Question 22

What part of the mucosa is ideal for bio-adhesives?

Question 23

What are the advantages of bioadhesive systems? 

Question 24

What are the mechanisms of bio-adhesion? 

Question 25

What are barriers to drug delivery of the ear?