Ear and Orphanyx Flashcards
What is the definition for sublingual drug delivery, buccal drug delivery and local drug delivery?
What type of epithelium are present in the oral cavity and where are they located?
what is the benefit of keratinised layer?
What is oral transmucosal drug delivery?
What are the advantages and disadvantages of transmucosal drug delivery?
What are the three main parts of the pharynx?
What are the physiological barriers affecting oral transmucosal drug delivery?
What is mucoadhesion?
Which part of the mouth produces a watery secretion of the mouth?
What is the difference between the paracellular route vs the transcellular route?
What region of the oral mucosa has the greatest epithelial thickness?
What are the two types of epithelial?
Which route allows for a larger drug delivery absorption and what characteristic gives it this trait?
Which route is likely to allow the drug into the systemic circulation?
What issues do we have with semi-solid dosage forms?
What is the mode of action for chewing gums?
What barrier is predominantly present for chewing gum formulation?
What are solid dosage formulations? What is a disadvantage of this formulation?
What are the bioadhesive formulations?
What are the advantages of the spray?
What can we do to optimize the formulations?
What part of the mucosa is ideal for bio-adhesives?
What are the advantages of bioadhesive systems?
What are the mechanisms of bio-adhesion?
What are barriers to drug delivery of the ear?
